Age-associated alterations in the recruitment of signal-transduction proteins to lipid rafts in human T lymphocytes

Aging is associated with a decline in T cell activation and proliferation, but the underlying mechanisms are not fully understood. Recent findings suggest that lipid rafts act as a platform in the initiation of T cell activation by selectively recruiting signaling proteins associated with formation...

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Veröffentlicht in:Journal of leukocyte biology 2004-02, Vol.75 (2), p.373-381
Hauptverfasser: Larbi, Anis, Douziech, Nadine, Dupuis, Gilles, Khalil, Abdelouahed, Pelletier, Hugues, Guerard, Karl‐Philippe, Fülöp, Tamàs
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Sprache:eng
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