Fibrillin and other matrix proteins in mitral valve prolapse syndrome

Unlike myxomatous degeneration in Marfan syndrome, which has been reported to result from a mutation in the gene that codes for the extracellular structural protein fibrillin, no specific molecular abnormality has been documented to be the underlying cause of myxomatous degeneration in mitral valve...

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Veröffentlicht in:	The Annals of thoracic surgery 2004-02, Vol.77 (2), p.532-536
Hauptverfasser:	Nasuti, Joseph F, Zhang, Paul J, Feldman, Michael D, Pasha, Terri, Khurana, Jasvir S, Gorman, Joseph H, Gorman, Robert C, Narula, Jagat, Narula, Navneet
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Biological and medical sciences Cardiology. Vascular system Collagen Type I - analysis Collagen Type III - analysis Elastin - analysis Extracellular Matrix - pathology Extracellular Matrix Proteins - analysis Female Fibrillins Humans Immunoenzyme Techniques Male Medical sciences Microfilament Proteins - analysis Middle Aged Mitral Valve - pathology Mitral Valve Prolapse - pathology Pneumology Reference Values Rheumatic Heart Disease - pathology
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