Mice lacking osteopontin exhibit increased left ventricular dilation and reduced fibrosis after aldosterone infusion

Osteopontin, also known as cytokine Eta-1, plays an important role in postmyocardial infarction remodeling by regulating collagen accumulation. Aldosterone promotes collagen synthesis and structural remodeling of the heart. The role of osteopontin in aldosterone-induced fibrosis and myocardial remod...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	American journal of hypertension 2004-02, Vol.17 (2), p.188-193
Hauptverfasser:	Sam, Flora, Xie, Zhonglin, Ooi, Henry, Kerstetter, David L, Colucci, Wilson S, Singh, Mahipal, Singh, Krishna
Format:	Artikel
Sprache:	eng
Schlagworte:	aldosterone Aldosterone - pharmacology Animals Apoptosis Arterial hypertension. Arterial hypotension Biological and medical sciences Blood and lymphatic vessels Blood Pressure Cardiology. Vascular system Dilatation, Pathologic - diagnostic imaging Disease Models, Animal Echocardiography Fibrosis Heart Heart - drug effects Immunohistochemistry Medical sciences Mice Myocardium - metabolism Myocardium - pathology Osteopontin Sialoglycoproteins - metabolism Ventricular Remodeling - drug effects Ventricular Remodeling - physiology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!