Flexor tendon wound healing in vitro: Lactate up-regulation of TGF-β expression and functional activity

Flexor tendon wound healing in zone II is complicated by adhesions to the surrounding fibro-osseous sheath. These adhesions can significantly alter tendon gliding and ultimately hand function. Lactate and transforming growth factor-beta (TGF-beta) are two important mediators of wound healing that ha...

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Veröffentlicht in:	Plastic and reconstructive surgery (1963) 2004-02, Vol.113 (2), p.625-632
Hauptverfasser:	YALAMANCHI, Naveen, KLEIN, Matthew B, PHAM, Hung M, LONGAKER, Michael T, CHANG, James
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Biological Assay Cell Line Cells, Cultured Enzyme-Linked Immunosorbent Assay Forelimb Lactic Acid - pharmacology Male Medical sciences Rabbits Receptors, Transforming Growth Factor beta - biosynthesis Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Tendon Injuries - metabolism Tendons - cytology Tendons - metabolism Transforming Growth Factor beta - biosynthesis Transforming Growth Factor beta - pharmacology Up-Regulation Wound Healing
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