Multiple rhabdomyomatous mesenchymal hamartomas of skin
A case of multiple rhabdomyomatous mesenchymal hamartomas is presented. The patient is a black male infant, the product of an uncomplicated term gestation and delivery. At birth, there were numerous polyps distributed over the periorbital and periauricular areas bilaterally. Some appeared fingerlike...
Gespeichert in:
| Veröffentlicht in: | The American journal of dermatopathology 1990-10, Vol.12 (5), p.485-491 |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 491 |
|---|---|
| container_issue | 5 |
| container_start_page | 485 |
| container_title | The American journal of dermatopathology |
| container_volume | 12 |
| creator | SAHN, E. E GAREN, P. D SHASHIDHAR PAI, G LEVKOFF, A. H HAGERTY, R. C MAIZE, J. C |
| description | A case of multiple rhabdomyomatous mesenchymal hamartomas is presented. The patient is a black male infant, the product of an uncomplicated term gestation and delivery. At birth, there were numerous polyps distributed over the periorbital and periauricular areas bilaterally. Some appeared fingerlike with constrictions below their tips. Others were branched or globular in shape. These projections showed spontaneous and independent movement, particularly during feedings. On histopathologic examination, the polyps were covered by squamous epithelium and contained normal follicular units. Bundles of skeletal muscle were present in the reticular dermis, extending into the subcutis. Regular cross-striations were seen in these muscle fibers. In some specimens, the muscle bundles formed a solid, central core. Skeletal muscle histochemical stains confirmed the presence of both types 1 and 2 muscle fibers. Electron microscopy revealed a normal skeletal muscle banding pattern. This case is the first report of multiple rhabdomyomatous mesenchymal hamartomas of skin. Functional skeletal muscle with spontaneous movement is part of the clinical picture. |
| doi_str_mv | 10.1097/00000372-199010000-00009 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_80129753</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>80129753</sourcerecordid><originalsourceid>FETCH-LOGICAL-c340t-caf49a3875c4ff551a5477a90ed7b60416ddd2cf33c87a0f1224f55b9ab013483</originalsourceid><addsrcrecordid>eNpFkMtOwzAQRS0EKqXwCUjZwM4wEztxvESIl1TEBtbRxLHVQB4lThb9exwaihe27Dt3fOcwFiHcIGh1C9MSKuaoNeB04dOmj9gSEyE4CMRjtgTUggcDnrIz7z8BMM4gWbBFHEuZpnLJ1OtYD9W2tlG_oaLsml3X0NCNPmqst63Z7Bqqow011A9B8VHnIv9VtefsxFHt7cV8rtjH48P7_TNfvz293N-tuRESBm7ISU0iU4mRziUJUiKVIg22VEUKEtOyLGPjhDCZInAYgoWyQlMBKGQmVux633fbd9-j9UPeVN7YuqbWhpR5FkbSKoy8Ytm-0PSd9711-bavQupdjpBPzPI_ZvmB2e-TDtbL-Y-xaGx5MM6Qgn416-QN1a6n1lT-v78OUKUG8QOOjHN6</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>80129753</pqid></control><display><type>article</type><title>Multiple rhabdomyomatous mesenchymal hamartomas of skin</title><source>MEDLINE</source><source>Journals@Ovid Complete</source><creator>SAHN, E. E ; GAREN, P. D ; SHASHIDHAR PAI, G ; LEVKOFF, A. H ; HAGERTY, R. C ; MAIZE, J. C</creator><creatorcontrib>SAHN, E. E ; GAREN, P. D ; SHASHIDHAR PAI, G ; LEVKOFF, A. H ; HAGERTY, R. C ; MAIZE, J. C</creatorcontrib><description>A case of multiple rhabdomyomatous mesenchymal hamartomas is presented. The patient is a black male infant, the product of an uncomplicated term gestation and delivery. At birth, there were numerous polyps distributed over the periorbital and periauricular areas bilaterally. Some appeared fingerlike with constrictions below their tips. Others were branched or globular in shape. These projections showed spontaneous and independent movement, particularly during feedings. On histopathologic examination, the polyps were covered by squamous epithelium and contained normal follicular units. Bundles of skeletal muscle were present in the reticular dermis, extending into the subcutis. Regular cross-striations were seen in these muscle fibers. In some specimens, the muscle bundles formed a solid, central core. Skeletal muscle histochemical stains confirmed the presence of both types 1 and 2 muscle fibers. Electron microscopy revealed a normal skeletal muscle banding pattern. This case is the first report of multiple rhabdomyomatous mesenchymal hamartomas of skin. Functional skeletal muscle with spontaneous movement is part of the clinical picture.</description><identifier>ISSN: 0193-1091</identifier><identifier>EISSN: 1533-0311</identifier><identifier>DOI: 10.1097/00000372-199010000-00009</identifier><identifier>PMID: 2244664</identifier><identifier>CODEN: AJODDB</identifier><language>eng</language><publisher>Hagerstown, MD: Lippincott Williams & Wilkins</publisher><subject>Biological and medical sciences ; Dermatology ; Diagnosis, Differential ; Facial Neoplasms - pathology ; Facial Neoplasms - ultrastructure ; Hamartoma Syndrome, Multiple - pathology ; Humans ; Infant, Newborn ; Male ; Medical sciences ; Muscles - pathology ; Muscles - ultrastructure ; Rhabdomyoma - pathology ; Skin Neoplasms - pathology ; Skin Neoplasms - ultrastructure ; Tumors of the skin and soft tissue. Premalignant lesions</subject><ispartof>The American journal of dermatopathology, 1990-10, Vol.12 (5), p.485-491</ispartof><rights>1991 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c340t-caf49a3875c4ff551a5477a90ed7b60416ddd2cf33c87a0f1224f55b9ab013483</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27903,27904</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=19280490$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/2244664$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>SAHN, E. E</creatorcontrib><creatorcontrib>GAREN, P. D</creatorcontrib><creatorcontrib>SHASHIDHAR PAI, G</creatorcontrib><creatorcontrib>LEVKOFF, A. H</creatorcontrib><creatorcontrib>HAGERTY, R. C</creatorcontrib><creatorcontrib>MAIZE, J. C</creatorcontrib><title>Multiple rhabdomyomatous mesenchymal hamartomas of skin</title><title>The American journal of dermatopathology</title><addtitle>Am J Dermatopathol</addtitle><description>A case of multiple rhabdomyomatous mesenchymal hamartomas is presented. The patient is a black male infant, the product of an uncomplicated term gestation and delivery. At birth, there were numerous polyps distributed over the periorbital and periauricular areas bilaterally. Some appeared fingerlike with constrictions below their tips. Others were branched or globular in shape. These projections showed spontaneous and independent movement, particularly during feedings. On histopathologic examination, the polyps were covered by squamous epithelium and contained normal follicular units. Bundles of skeletal muscle were present in the reticular dermis, extending into the subcutis. Regular cross-striations were seen in these muscle fibers. In some specimens, the muscle bundles formed a solid, central core. Skeletal muscle histochemical stains confirmed the presence of both types 1 and 2 muscle fibers. Electron microscopy revealed a normal skeletal muscle banding pattern. This case is the first report of multiple rhabdomyomatous mesenchymal hamartomas of skin. Functional skeletal muscle with spontaneous movement is part of the clinical picture.</description><subject>Biological and medical sciences</subject><subject>Dermatology</subject><subject>Diagnosis, Differential</subject><subject>Facial Neoplasms - pathology</subject><subject>Facial Neoplasms - ultrastructure</subject><subject>Hamartoma Syndrome, Multiple - pathology</subject><subject>Humans</subject><subject>Infant, Newborn</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Muscles - pathology</subject><subject>Muscles - ultrastructure</subject><subject>Rhabdomyoma - pathology</subject><subject>Skin Neoplasms - pathology</subject><subject>Skin Neoplasms - ultrastructure</subject><subject>Tumors of the skin and soft tissue. Premalignant lesions</subject><issn>0193-1091</issn><issn>1533-0311</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1990</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpFkMtOwzAQRS0EKqXwCUjZwM4wEztxvESIl1TEBtbRxLHVQB4lThb9exwaihe27Dt3fOcwFiHcIGh1C9MSKuaoNeB04dOmj9gSEyE4CMRjtgTUggcDnrIz7z8BMM4gWbBFHEuZpnLJ1OtYD9W2tlG_oaLsml3X0NCNPmqst63Z7Bqqow011A9B8VHnIv9VtefsxFHt7cV8rtjH48P7_TNfvz293N-tuRESBm7ISU0iU4mRziUJUiKVIg22VEUKEtOyLGPjhDCZInAYgoWyQlMBKGQmVux633fbd9-j9UPeVN7YuqbWhpR5FkbSKoy8Ytm-0PSd9711-bavQupdjpBPzPI_ZvmB2e-TDtbL-Y-xaGx5MM6Qgn416-QN1a6n1lT-v78OUKUG8QOOjHN6</recordid><startdate>19901001</startdate><enddate>19901001</enddate><creator>SAHN, E. E</creator><creator>GAREN, P. D</creator><creator>SHASHIDHAR PAI, G</creator><creator>LEVKOFF, A. H</creator><creator>HAGERTY, R. C</creator><creator>MAIZE, J. C</creator><general>Lippincott Williams & Wilkins</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19901001</creationdate><title>Multiple rhabdomyomatous mesenchymal hamartomas of skin</title><author>SAHN, E. E ; GAREN, P. D ; SHASHIDHAR PAI, G ; LEVKOFF, A. H ; HAGERTY, R. C ; MAIZE, J. C</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c340t-caf49a3875c4ff551a5477a90ed7b60416ddd2cf33c87a0f1224f55b9ab013483</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1990</creationdate><topic>Biological and medical sciences</topic><topic>Dermatology</topic><topic>Diagnosis, Differential</topic><topic>Facial Neoplasms - pathology</topic><topic>Facial Neoplasms - ultrastructure</topic><topic>Hamartoma Syndrome, Multiple - pathology</topic><topic>Humans</topic><topic>Infant, Newborn</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Muscles - pathology</topic><topic>Muscles - ultrastructure</topic><topic>Rhabdomyoma - pathology</topic><topic>Skin Neoplasms - pathology</topic><topic>Skin Neoplasms - ultrastructure</topic><topic>Tumors of the skin and soft tissue. Premalignant lesions</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>SAHN, E. E</creatorcontrib><creatorcontrib>GAREN, P. D</creatorcontrib><creatorcontrib>SHASHIDHAR PAI, G</creatorcontrib><creatorcontrib>LEVKOFF, A. H</creatorcontrib><creatorcontrib>HAGERTY, R. C</creatorcontrib><creatorcontrib>MAIZE, J. C</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>The American journal of dermatopathology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>SAHN, E. E</au><au>GAREN, P. D</au><au>SHASHIDHAR PAI, G</au><au>LEVKOFF, A. H</au><au>HAGERTY, R. C</au><au>MAIZE, J. C</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Multiple rhabdomyomatous mesenchymal hamartomas of skin</atitle><jtitle>The American journal of dermatopathology</jtitle><addtitle>Am J Dermatopathol</addtitle><date>1990-10-01</date><risdate>1990</risdate><volume>12</volume><issue>5</issue><spage>485</spage><epage>491</epage><pages>485-491</pages><issn>0193-1091</issn><eissn>1533-0311</eissn><coden>AJODDB</coden><abstract>A case of multiple rhabdomyomatous mesenchymal hamartomas is presented. The patient is a black male infant, the product of an uncomplicated term gestation and delivery. At birth, there were numerous polyps distributed over the periorbital and periauricular areas bilaterally. Some appeared fingerlike with constrictions below their tips. Others were branched or globular in shape. These projections showed spontaneous and independent movement, particularly during feedings. On histopathologic examination, the polyps were covered by squamous epithelium and contained normal follicular units. Bundles of skeletal muscle were present in the reticular dermis, extending into the subcutis. Regular cross-striations were seen in these muscle fibers. In some specimens, the muscle bundles formed a solid, central core. Skeletal muscle histochemical stains confirmed the presence of both types 1 and 2 muscle fibers. Electron microscopy revealed a normal skeletal muscle banding pattern. This case is the first report of multiple rhabdomyomatous mesenchymal hamartomas of skin. Functional skeletal muscle with spontaneous movement is part of the clinical picture.</abstract><cop>Hagerstown, MD</cop><pub>Lippincott Williams & Wilkins</pub><pmid>2244664</pmid><doi>10.1097/00000372-199010000-00009</doi><tpages>7</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0193-1091 |
| ispartof | The American journal of dermatopathology, 1990-10, Vol.12 (5), p.485-491 |
| issn | 0193-1091 1533-0311 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_80129753 |
| source | MEDLINE; Journals@Ovid Complete |
| subjects | Biological and medical sciences Dermatology Diagnosis, Differential Facial Neoplasms - pathology Facial Neoplasms - ultrastructure Hamartoma Syndrome, Multiple - pathology Humans Infant, Newborn Male Medical sciences Muscles - pathology Muscles - ultrastructure Rhabdomyoma - pathology Skin Neoplasms - pathology Skin Neoplasms - ultrastructure Tumors of the skin and soft tissue. Premalignant lesions |
| title | Multiple rhabdomyomatous mesenchymal hamartomas of skin |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-26T08%3A43%3A01IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Multiple%20rhabdomyomatous%20mesenchymal%20hamartomas%20of%20skin&rft.jtitle=The%20American%20journal%20of%20dermatopathology&rft.au=SAHN,%20E.%20E&rft.date=1990-10-01&rft.volume=12&rft.issue=5&rft.spage=485&rft.epage=491&rft.pages=485-491&rft.issn=0193-1091&rft.eissn=1533-0311&rft.coden=AJODDB&rft_id=info:doi/10.1097/00000372-199010000-00009&rft_dat=%3Cproquest_cross%3E80129753%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=80129753&rft_id=info:pmid/2244664&rfr_iscdi=true |