Geographic distribution of prostate cancer incidence in the era of PSA testing, Connecticut, 1984 to 1998

To evaluate the geographic variation of prostate cancer incidence in Connecticut during a 15-year period: before the introduction of prostate-specific antigen (PSA) testing (1984 to 1988), during its introduction (1989 to 1993), and after its widespread adoption (1994 to 1998). A spatial scan statis...

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Veröffentlicht in:Urology (Ridgewood, N.J.) N.J.), 2004, Vol.63 (1), p.78-82
Hauptverfasser: Gregorio, David I., Kulldorff, Martin, Sheehan, T.Joseph, Samociuk, Holly
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container_title Urology (Ridgewood, N.J.)
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creator Gregorio, David I.
Kulldorff, Martin
Sheehan, T.Joseph
Samociuk, Holly
description To evaluate the geographic variation of prostate cancer incidence in Connecticut during a 15-year period: before the introduction of prostate-specific antigen (PSA) testing (1984 to 1988), during its introduction (1989 to 1993), and after its widespread adoption (1994 to 1998). A spatial scan statistic was used to detect and test the significance of the geographic rate variation among 29,944 incident cases. During 1984 to 1988, eight locations had incidence rates that differed significantly from the statewide level; for 1989 to 1993, only two locations were identified. By 1994 to 1998, a significant rate variation was noted for 10 locations around Connecticut. The observed geographic variation of incidence rates may reflect differing opportunities to uncover latent cases at given locales.
doi_str_mv 10.1016/j.urology.2003.08.008
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Obstetrics</subject><subject>Humans</subject><subject>Incidence</subject><subject>Male</subject><subject>Male genital diseases</subject><subject>Mass Screening</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Neoplasm Proteins - blood</subject><subject>Nephrology. Urinary tract diseases</subject><subject>Prostate-Specific Antigen - blood</subject><subject>Prostatic Neoplasms - blood</subject><subject>Prostatic Neoplasms - diagnosis</subject><subject>Prostatic Neoplasms - epidemiology</subject><subject>SEER Program - statistics &amp; numerical data</subject><subject>Tumors</subject><subject>Tumors of the urinary system</subject><subject>Urinary tract. 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A spatial scan statistic was used to detect and test the significance of the geographic rate variation among 29,944 incident cases. During 1984 to 1988, eight locations had incidence rates that differed significantly from the statewide level; for 1989 to 1993, only two locations were identified. By 1994 to 1998, a significant rate variation was noted for 10 locations around Connecticut. The observed geographic variation of incidence rates may reflect differing opportunities to uncover latent cases at given locales.</abstract><cop>New York, NY</cop><pub>Elsevier Inc</pub><pmid>14751353</pmid><doi>10.1016/j.urology.2003.08.008</doi><tpages>5</tpages></addata></record>
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subjects Adenocarcinoma - blood
Adenocarcinoma - diagnosis
Adenocarcinoma - epidemiology
Adult
Aged
Aged, 80 and over
Biological and medical sciences
Biomarkers, Tumor - blood
Cluster Analysis
Connecticut - epidemiology
Diagnostic Tests, Routine - statistics & numerical data
Diagnostic Tests, Routine - trends
Early Diagnosis
Gynecology. Andrology. Obstetrics
Humans
Incidence
Male
Male genital diseases
Mass Screening
Medical sciences
Middle Aged
Neoplasm Proteins - blood
Nephrology. Urinary tract diseases
Prostate-Specific Antigen - blood
Prostatic Neoplasms - blood
Prostatic Neoplasms - diagnosis
Prostatic Neoplasms - epidemiology
SEER Program - statistics & numerical data
Tumors
Tumors of the urinary system
Urinary tract. Prostate gland
title Geographic distribution of prostate cancer incidence in the era of PSA testing, Connecticut, 1984 to 1998
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