Geographic distribution of prostate cancer incidence in the era of PSA testing, Connecticut, 1984 to 1998
To evaluate the geographic variation of prostate cancer incidence in Connecticut during a 15-year period: before the introduction of prostate-specific antigen (PSA) testing (1984 to 1988), during its introduction (1989 to 1993), and after its widespread adoption (1994 to 1998). A spatial scan statis...
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Veröffentlicht in: | Urology (Ridgewood, N.J.) N.J.), 2004, Vol.63 (1), p.78-82 |
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creator | Gregorio, David I. Kulldorff, Martin Sheehan, T.Joseph Samociuk, Holly |
description | To evaluate the geographic variation of prostate cancer incidence in Connecticut during a 15-year period: before the introduction of prostate-specific antigen (PSA) testing (1984 to 1988), during its introduction (1989 to 1993), and after its widespread adoption (1994 to 1998).
A spatial scan statistic was used to detect and test the significance of the geographic rate variation among 29,944 incident cases.
During 1984 to 1988, eight locations had incidence rates that differed significantly from the statewide level; for 1989 to 1993, only two locations were identified. By 1994 to 1998, a significant rate variation was noted for 10 locations around Connecticut.
The observed geographic variation of incidence rates may reflect differing opportunities to uncover latent cases at given locales. |
doi_str_mv | 10.1016/j.urology.2003.08.008 |
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A spatial scan statistic was used to detect and test the significance of the geographic rate variation among 29,944 incident cases.
During 1984 to 1988, eight locations had incidence rates that differed significantly from the statewide level; for 1989 to 1993, only two locations were identified. By 1994 to 1998, a significant rate variation was noted for 10 locations around Connecticut.
The observed geographic variation of incidence rates may reflect differing opportunities to uncover latent cases at given locales.</description><identifier>ISSN: 0090-4295</identifier><identifier>EISSN: 1527-9995</identifier><identifier>DOI: 10.1016/j.urology.2003.08.008</identifier><identifier>PMID: 14751353</identifier><identifier>CODEN: URGYAZ</identifier><language>eng</language><publisher>New York, NY: Elsevier Inc</publisher><subject>Adenocarcinoma - blood ; Adenocarcinoma - diagnosis ; Adenocarcinoma - epidemiology ; Adult ; Aged ; Aged, 80 and over ; Biological and medical sciences ; Biomarkers, Tumor - blood ; Cluster Analysis ; Connecticut - epidemiology ; Diagnostic Tests, Routine - statistics & numerical data ; Diagnostic Tests, Routine - trends ; Early Diagnosis ; Gynecology. Andrology. Obstetrics ; Humans ; Incidence ; Male ; Male genital diseases ; Mass Screening ; Medical sciences ; Middle Aged ; Neoplasm Proteins - blood ; Nephrology. Urinary tract diseases ; Prostate-Specific Antigen - blood ; Prostatic Neoplasms - blood ; Prostatic Neoplasms - diagnosis ; Prostatic Neoplasms - epidemiology ; SEER Program - statistics & numerical data ; Tumors ; Tumors of the urinary system ; Urinary tract. Prostate gland</subject><ispartof>Urology (Ridgewood, N.J.), 2004, Vol.63 (1), p.78-82</ispartof><rights>2004 Elsevier Inc.</rights><rights>2004 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c391t-5c4a03789a47247a69f3e45939d6b5639bcdc8a334c9b5a12bcc040ca19113783</citedby><cites>FETCH-LOGICAL-c391t-5c4a03789a47247a69f3e45939d6b5639bcdc8a334c9b5a12bcc040ca19113783</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0090429503008872$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,4010,27902,27903,27904,65309</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=15572841$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/14751353$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Gregorio, David I.</creatorcontrib><creatorcontrib>Kulldorff, Martin</creatorcontrib><creatorcontrib>Sheehan, T.Joseph</creatorcontrib><creatorcontrib>Samociuk, Holly</creatorcontrib><title>Geographic distribution of prostate cancer incidence in the era of PSA testing, Connecticut, 1984 to 1998</title><title>Urology (Ridgewood, N.J.)</title><addtitle>Urology</addtitle><description>To evaluate the geographic variation of prostate cancer incidence in Connecticut during a 15-year period: before the introduction of prostate-specific antigen (PSA) testing (1984 to 1988), during its introduction (1989 to 1993), and after its widespread adoption (1994 to 1998).
A spatial scan statistic was used to detect and test the significance of the geographic rate variation among 29,944 incident cases.
During 1984 to 1988, eight locations had incidence rates that differed significantly from the statewide level; for 1989 to 1993, only two locations were identified. By 1994 to 1998, a significant rate variation was noted for 10 locations around Connecticut.
The observed geographic variation of incidence rates may reflect differing opportunities to uncover latent cases at given locales.</description><subject>Adenocarcinoma - blood</subject><subject>Adenocarcinoma - diagnosis</subject><subject>Adenocarcinoma - epidemiology</subject><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Biological and medical sciences</subject><subject>Biomarkers, Tumor - blood</subject><subject>Cluster Analysis</subject><subject>Connecticut - epidemiology</subject><subject>Diagnostic Tests, Routine - statistics & numerical data</subject><subject>Diagnostic Tests, Routine - trends</subject><subject>Early Diagnosis</subject><subject>Gynecology. Andrology. Obstetrics</subject><subject>Humans</subject><subject>Incidence</subject><subject>Male</subject><subject>Male genital diseases</subject><subject>Mass Screening</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Neoplasm Proteins - blood</subject><subject>Nephrology. Urinary tract diseases</subject><subject>Prostate-Specific Antigen - blood</subject><subject>Prostatic Neoplasms - blood</subject><subject>Prostatic Neoplasms - diagnosis</subject><subject>Prostatic Neoplasms - epidemiology</subject><subject>SEER Program - statistics & numerical data</subject><subject>Tumors</subject><subject>Tumors of the urinary system</subject><subject>Urinary tract. Prostate gland</subject><issn>0090-4295</issn><issn>1527-9995</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2004</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkMFu1DAQhi0EokvpI4B8gVMTxrGd2CdUrdqCVAkk6NlyJs7Wq2y82A5S3x6vNlKPnGYO32__8xHygUHNgLVf9vUSwxR2z3UDwGtQNYB6RTZMNl2ltZavyQZAQyUaLS_Iu5T2ANC2bfeWXDDRScYl3xB_78Iu2uOTRzr4lKPvl-zDTMNIjzGkbLOjaGd0kfoZ_eDKWjaanxx10Z64n79uaHYp-3l3Tbdhnh1mj0u-pkwrQXMoU6v35M1op-Su1nlJHu9uf2-_VQ8_7r9vbx4q5JrlSqKwwDulrega0dlWj9wJqbke2l62XPc4oLKcC9S9tKzpEUEAWqYZKzl-ST6f3y31_yylljn4hG6a7OzCkowC1iit2gLKM4jlzhTdaI7RH2x8NgzMybHZm9WxOTk2oExxXHIf1w-W_uCGl9QqtQCfVsAmtNMYiz6fXjgpu0YJVrivZ84VHX-9iyahP_kdfCwKzRD8f6r8A1Y7m50</recordid><startdate>2004</startdate><enddate>2004</enddate><creator>Gregorio, David I.</creator><creator>Kulldorff, Martin</creator><creator>Sheehan, T.Joseph</creator><creator>Samociuk, Holly</creator><general>Elsevier Inc</general><general>Elsevier Science</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>2004</creationdate><title>Geographic distribution of prostate cancer incidence in the era of PSA testing, Connecticut, 1984 to 1998</title><author>Gregorio, David I. ; Kulldorff, Martin ; Sheehan, T.Joseph ; Samociuk, Holly</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c391t-5c4a03789a47247a69f3e45939d6b5639bcdc8a334c9b5a12bcc040ca19113783</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2004</creationdate><topic>Adenocarcinoma - blood</topic><topic>Adenocarcinoma - diagnosis</topic><topic>Adenocarcinoma - epidemiology</topic><topic>Adult</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Biological and medical sciences</topic><topic>Biomarkers, Tumor - blood</topic><topic>Cluster Analysis</topic><topic>Connecticut - epidemiology</topic><topic>Diagnostic Tests, Routine - statistics & numerical data</topic><topic>Diagnostic Tests, Routine - trends</topic><topic>Early Diagnosis</topic><topic>Gynecology. Andrology. Obstetrics</topic><topic>Humans</topic><topic>Incidence</topic><topic>Male</topic><topic>Male genital diseases</topic><topic>Mass Screening</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Neoplasm Proteins - blood</topic><topic>Nephrology. Urinary tract diseases</topic><topic>Prostate-Specific Antigen - blood</topic><topic>Prostatic Neoplasms - blood</topic><topic>Prostatic Neoplasms - diagnosis</topic><topic>Prostatic Neoplasms - epidemiology</topic><topic>SEER Program - statistics & numerical data</topic><topic>Tumors</topic><topic>Tumors of the urinary system</topic><topic>Urinary tract. Prostate gland</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Gregorio, David I.</creatorcontrib><creatorcontrib>Kulldorff, Martin</creatorcontrib><creatorcontrib>Sheehan, T.Joseph</creatorcontrib><creatorcontrib>Samociuk, Holly</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Urology (Ridgewood, N.J.)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Gregorio, David I.</au><au>Kulldorff, Martin</au><au>Sheehan, T.Joseph</au><au>Samociuk, Holly</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Geographic distribution of prostate cancer incidence in the era of PSA testing, Connecticut, 1984 to 1998</atitle><jtitle>Urology (Ridgewood, N.J.)</jtitle><addtitle>Urology</addtitle><date>2004</date><risdate>2004</risdate><volume>63</volume><issue>1</issue><spage>78</spage><epage>82</epage><pages>78-82</pages><issn>0090-4295</issn><eissn>1527-9995</eissn><coden>URGYAZ</coden><abstract>To evaluate the geographic variation of prostate cancer incidence in Connecticut during a 15-year period: before the introduction of prostate-specific antigen (PSA) testing (1984 to 1988), during its introduction (1989 to 1993), and after its widespread adoption (1994 to 1998).
A spatial scan statistic was used to detect and test the significance of the geographic rate variation among 29,944 incident cases.
During 1984 to 1988, eight locations had incidence rates that differed significantly from the statewide level; for 1989 to 1993, only two locations were identified. By 1994 to 1998, a significant rate variation was noted for 10 locations around Connecticut.
The observed geographic variation of incidence rates may reflect differing opportunities to uncover latent cases at given locales.</abstract><cop>New York, NY</cop><pub>Elsevier Inc</pub><pmid>14751353</pmid><doi>10.1016/j.urology.2003.08.008</doi><tpages>5</tpages></addata></record> |
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subjects | Adenocarcinoma - blood Adenocarcinoma - diagnosis Adenocarcinoma - epidemiology Adult Aged Aged, 80 and over Biological and medical sciences Biomarkers, Tumor - blood Cluster Analysis Connecticut - epidemiology Diagnostic Tests, Routine - statistics & numerical data Diagnostic Tests, Routine - trends Early Diagnosis Gynecology. Andrology. Obstetrics Humans Incidence Male Male genital diseases Mass Screening Medical sciences Middle Aged Neoplasm Proteins - blood Nephrology. Urinary tract diseases Prostate-Specific Antigen - blood Prostatic Neoplasms - blood Prostatic Neoplasms - diagnosis Prostatic Neoplasms - epidemiology SEER Program - statistics & numerical data Tumors Tumors of the urinary system Urinary tract. Prostate gland |
title | Geographic distribution of prostate cancer incidence in the era of PSA testing, Connecticut, 1984 to 1998 |
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