NOXO1, Regulation of Lipid Binding, Localization, and Activation of Nox1 by the Phox Homology (PX) Domain

NOXO1 (Nox organizing protein 1) and NOXA1 (Nox activating protein 1) are homologs of p47phox and p67phox. p47phox functions in phagocytes as an essential organizing protein mediating the binding of other regulatory proteins during activation of the phagocyte oxidase, and its translocation to the me...

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Veröffentlicht in:	The Journal of biological chemistry 2004-02, Vol.279 (6), p.4737-4742
Hauptverfasser:	Cheng, Guangjie, Lambeth, J. David
Format:	Artikel
Sprache:	eng
Schlagworte:	Adaptor Proteins, Signal Transducing Adaptor Proteins, Vesicular Transport - chemistry Adaptor Proteins, Vesicular Transport - genetics Adaptor Proteins, Vesicular Transport - metabolism Animals Cell Line Enzyme Activation Humans membrane lipids Membrane Lipids - metabolism Mice NADPH Oxidase 1 NADPH Oxidases - genetics NADPH Oxidases - metabolism NIH 3T3 Cells NOXA1 protein NOXO1 protein Phagocytes - metabolism Phosphoproteins - genetics Phosphoproteins - metabolism Point Mutation Protein Binding Protein Structure, Tertiary Reactive Oxygen Species - metabolism Recombinant Fusion Proteins - chemistry Recombinant Fusion Proteins - genetics Recombinant Fusion Proteins - metabolism Transfection
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