Role of Adrenergic Activity in Pressor Responses to Chronic Melanocortin Receptor Activation

ABSTRACT—Acute studies have shown that MC3/4-R stimulation increases sympathetic activity, but the role of adrenergic activation in mediating the cardiovascular and renal responses to chronic melanocortin 3- and 4-receptor (MC3/4-R) activation is unknown. The present study tested whether chronic MC3...

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Veröffentlicht in:	Hypertension (Dallas, Tex. 1979) Tex. 1979), 2004-02, Vol.43 (2, Part 2), p.370-375
Hauptverfasser:	Kuo, Jay J, da Silva, Alexandre A, Tallam, Lakshmi S, Hall, John E
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenergic Antagonists - pharmacology alpha-MSH - analogs & derivatives alpha-MSH - pharmacology Animals Arterial hypertension. Arterial hypotension Biological and medical sciences Blood and lymphatic vessels Blood Pressure - drug effects Cardiology. Vascular system Clinical manifestations. Epidemiology. Investigative techniques. Etiology Eating - drug effects Fundamental and applied biological sciences. Psychology Heart Rate - drug effects Kidney - physiology Male Medical sciences Rats Rats, Sprague-Dawley Receptor, Melanocortin, Type 3 - agonists Receptor, Melanocortin, Type 4 - agonists Vertebrates: urinary system
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