Glypican-3 is involved in cellular protection against mitoxantrone in gastric carcinoma cells

Elevated expression of the heparan sulphate proteoglycan glypican-3 (GPC3) was found on mRNA and protein levels in the atypical multidrug-resistant gastric carcinoma cell line EPG85-257RNOV, which was established by in vitro selection against mitoxantrone. In order to elucidate a putative role of GP...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Oncogene 2004-01, Vol.23 (4), p.945-955
Hauptverfasser:	Wichert, Anke, Stege, Alexandra, Midorikawa, Yutaka, Holm, Per Sonne, Lage, Hermann
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic Agents - pharmacology Apoptosis Base Sequence Biological and medical sciences Cancer Cell Biology Cell Line, Tumor Cell physiology Cell transformation and carcinogenesis. Action of oncogenes and antioncogenes Cloning DNA Primers Drug resistance Flow Cytometry Fundamental and applied biological sciences. Psychology Genotype & phenotype Glypicans Heparan Sulfate Proteoglycans - genetics Heparan Sulfate Proteoglycans - physiology Human Genetics Humans Internal Medicine Medicine Medicine & Public Health Mitoxantrone - pharmacology Molecular and cellular biology Oncology original-paper Proteins RNA, Messenger - genetics Stomach Neoplasms - pathology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!