Alleviation of ischemic neuronal damage by histamine H2 receptor stimulation in the rat striatum

Transient ischemia was produced for 15 min by occlusion of the middle cerebral artery in halothane-anesthetized rats, and changes in the extracellular concentrations of neurotransmitter monoamines and amino acids were examined in the striatum. The occlusion produced marked increases in the extracell...

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Veröffentlicht in:	European journal of pharmacology 2004-01, Vol.484 (2-3), p.167-173
Hauptverfasser:	HAMAMI, Gen, ADACHI, Naoto, KEYUE LIU, ARAI, Tatsuru
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Brain Ischemia - drug therapy Brain Ischemia - metabolism Brain Ischemia - pathology Corpus Striatum - drug effects Corpus Striatum - metabolism Corpus Striatum - pathology Dopamine - metabolism Histamine - pharmacology Histamine - therapeutic use Male Medical sciences Neurons - drug effects Neurons - metabolism Neurons - pathology Pharmacology. Drug treatments Rats Rats, Wistar Receptors, Histamine H2 - metabolism
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