Positive tissue transglutaminase antibodies with negative endomysial antibodies: low rate of celiac disease

Screening for celiac disease is based on the sequential evaluation of serologic tests and intestinal biopsy; an optimal screening protocol is still under investigation. The screening policy of one of the main healthcare providers in Israel (Maccabi) consists of measuring total immunoglobulin A and t...

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Veröffentlicht in:	The Israel Medical Association journal 2004-01, Vol.6 (1), p.9-12
Hauptverfasser:	Weiss, Batia, Bujanover, Yoram, Avidan, Benjamin, Fradkin, Akiva, Weintraub, Ilana, Shainberg, Bracha
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Autoantibodies - analysis Autoantibodies - blood Bias Biomarkers - analysis Biomarkers - blood Biopsy - methods Biopsy - standards Celiac Disease - diagnosis Celiac Disease - epidemiology Celiac Disease - immunology Celiac Disease - metabolism Duodenum - enzymology Duodenum - immunology Duodenum - pathology Enzyme-Linked Immunosorbent Assay - methods Enzyme-Linked Immunosorbent Assay - standards Female Fluorescent Antibody Technique, Indirect Gliadin - immunology Humans Immunoglobulin A - analysis Immunoglobulin A - blood Immunoglobulin G - analysis Immunoglobulin G - blood Israel - epidemiology Male Mass Screening - methods Mass Screening - standards Prevalence Sensitivity and Specificity Transglutaminases - immunology
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