Synthesis and Pharmacological Studies of Some (1,4)-Naphthoquinono[3,2-c]-1H-pyrazoles,2-Substituted Amino-1,4-naphthoquinones, and Related Compounds
Series of (1,4)‐Naphthoquinono(3,2‐c)‐1H‐pyrazoles and 2‐substituted amino‐1,4‐naphthoquinones have been synthesised and studied for their possible anticancer activity (animal tumours, Walker 256 carcinosarcoma), Influenza RNA transcriptase activity, antibiotic activity (C. neoformans, T. mentagraph...
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| Veröffentlicht in: | Archiv der Pharmazie (Weinheim) 1990, Vol.323 (7), p.383-385 |
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| creator | Tandon, V. K. Vaish, Meenu Khanna, J. M. Anand, Nitya |
| description | Series of (1,4)‐Naphthoquinono(3,2‐c)‐1H‐pyrazoles and 2‐substituted amino‐1,4‐naphthoquinones have been synthesised and studied for their possible anticancer activity (animal tumours, Walker 256 carcinosarcoma), Influenza RNA transcriptase activity, antibiotic activity (C. neoformans, T. mentagraphytes, M. canis, A. niger, and C. albicans).
Synthese und pharmakologische Prüfung einiger (1,4)‐Naphthochinon‐[3,2‐c]‐1H‐pyrazole, 2‐substituierter Amino‐1,4‐naphthochinone und verwandter Verbindungen
1,4‐Naphthochinon[3,2‐c]‐1H‐pyrazole and 2‐substituierte Amino‐1,4‐naphthochinone wurden hergestellt und auf cytostatische Wirkung (Tiertumore, Walker 256 Sarkom)), Influenza RNS‐Transkriptase Aktivität und antibiotische Wirksamkeit (C. neoformans, T. mentagraphytes, M. canis, A. niger und C. albicans) geprüft. |
| doi_str_mv | 10.1002/ardp.19903230702 |
| format | Article |
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Synthese und pharmakologische Prüfung einiger (1,4)‐Naphthochinon‐[3,2‐c]‐1H‐pyrazole, 2‐substituierter Amino‐1,4‐naphthochinone und verwandter Verbindungen
1,4‐Naphthochinon[3,2‐c]‐1H‐pyrazole and 2‐substituierte Amino‐1,4‐naphthochinone wurden hergestellt und auf cytostatische Wirkung (Tiertumore, Walker 256 Sarkom)), Influenza RNS‐Transkriptase Aktivität und antibiotische Wirksamkeit (C. neoformans, T. mentagraphytes, M. canis, A. niger und C. albicans) geprüft.</description><identifier>ISSN: 0365-6233</identifier><identifier>EISSN: 1521-4184</identifier><identifier>DOI: 10.1002/ardp.19903230702</identifier><identifier>PMID: 2241532</identifier><identifier>CODEN: ARPMAS</identifier><language>eng</language><publisher>Hannover: WILEY-VCH Verlag</publisher><subject>Antineoplastic Agents - chemical synthesis ; Bacteria - drug effects ; Cells, Cultured ; Chemical Phenomena ; Chemistry ; Exact sciences and technology ; Fungi - drug effects ; Heterocyclic compounds ; Heterocyclic compounds with several n hetero atoms in the same ring, in separated rings or in fused rings ; Naphthoquinones - chemical synthesis ; Naphthoquinones - pharmacology ; Organic chemistry ; Preparations and properties ; Pyrazoles - chemical synthesis ; Pyrazoles - pharmacology</subject><ispartof>Archiv der Pharmazie (Weinheim), 1990, Vol.323 (7), p.383-385</ispartof><rights>Copyright © 1990 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim</rights><rights>1991 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4162-169f823f07d0ecaa191f8d2bbadbdf5ad881a9ee3a16a9685d843b6887a6330e3</citedby><cites>FETCH-LOGICAL-c4162-169f823f07d0ecaa191f8d2bbadbdf5ad881a9ee3a16a9685d843b6887a6330e3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Fardp.19903230702$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Fardp.19903230702$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,777,781,1412,4010,27904,27905,27906,45555,45556</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=19369496$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/2241532$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Tandon, V. K.</creatorcontrib><creatorcontrib>Vaish, Meenu</creatorcontrib><creatorcontrib>Khanna, J. M.</creatorcontrib><creatorcontrib>Anand, Nitya</creatorcontrib><title>Synthesis and Pharmacological Studies of Some (1,4)-Naphthoquinono[3,2-c]-1H-pyrazoles,2-Substituted Amino-1,4-naphthoquinones, and Related Compounds</title><title>Archiv der Pharmazie (Weinheim)</title><addtitle>Arch. Pharm. Pharm. Med. Chem</addtitle><description>Series of (1,4)‐Naphthoquinono(3,2‐c)‐1H‐pyrazoles and 2‐substituted amino‐1,4‐naphthoquinones have been synthesised and studied for their possible anticancer activity (animal tumours, Walker 256 carcinosarcoma), Influenza RNA transcriptase activity, antibiotic activity (C. neoformans, T. mentagraphytes, M. canis, A. niger, and C. albicans).
Synthese und pharmakologische Prüfung einiger (1,4)‐Naphthochinon‐[3,2‐c]‐1H‐pyrazole, 2‐substituierter Amino‐1,4‐naphthochinone und verwandter Verbindungen
1,4‐Naphthochinon[3,2‐c]‐1H‐pyrazole and 2‐substituierte Amino‐1,4‐naphthochinone wurden hergestellt und auf cytostatische Wirkung (Tiertumore, Walker 256 Sarkom)), Influenza RNS‐Transkriptase Aktivität und antibiotische Wirksamkeit (C. neoformans, T. mentagraphytes, M. canis, A. niger und C. albicans) geprüft.</description><subject>Antineoplastic Agents - chemical synthesis</subject><subject>Bacteria - drug effects</subject><subject>Cells, Cultured</subject><subject>Chemical Phenomena</subject><subject>Chemistry</subject><subject>Exact sciences and technology</subject><subject>Fungi - drug effects</subject><subject>Heterocyclic compounds</subject><subject>Heterocyclic compounds with several n hetero atoms in the same ring, in separated rings or in fused rings</subject><subject>Naphthoquinones - chemical synthesis</subject><subject>Naphthoquinones - pharmacology</subject><subject>Organic chemistry</subject><subject>Preparations and properties</subject><subject>Pyrazoles - chemical synthesis</subject><subject>Pyrazoles - pharmacology</subject><issn>0365-6233</issn><issn>1521-4184</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1990</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkU1v1DAQhi1EVZbCnQtSLlQg1cUfieMcOKwWaIFSSsOHBELWJHZYlyQOdqKy_A_-L152VcqJkyXP88yM5kXoHiWHlBD2GLweDmlREM44yQm7gWY0YxSnVKY30YxwkWHBOL-FbodwQQjhhGW7aJexlGaczdCvctWPSxNsSKDXydkSfAe1a91XW0OblOOkrQmJa5LSdSZ5SA_SR_gUhuW4dN8n27vefeYHDNdfMD3Gw8rDT9eaEH_KqQqjHafR6GTeRRJHF_fX1cj9mXpuWlhjC9cNbup1uIN2GmiDubt999D758_eLY7xyZujF4v5Ca5TKhimomgk4w3JNTE1AC1oIzWrKtCVbjLQUlIojOFABRRCZlqmvBJS5iA4J4bvof1N38HHlUwYVWdDbdoWeuOmoCShVGZSRpBswNq7ELxp1OBtB36lKFHrJNQ6CXUtiajc3_aeqs7oK2F7-lh_sK1DiKduPPS1DX_7FlwUaSEi92TDXdrWrP47V83Pn579uwfe-DaM5seVD_6bEjnPM_Xx9Ei9ev3p5VtRflCC_wbupbOA</recordid><startdate>1990</startdate><enddate>1990</enddate><creator>Tandon, V. K.</creator><creator>Vaish, Meenu</creator><creator>Khanna, J. M.</creator><creator>Anand, Nitya</creator><general>WILEY-VCH Verlag</general><general>WILEY‐VCH Verlag</general><general>Wiley-VCH</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>1990</creationdate><title>Synthesis and Pharmacological Studies of Some (1,4)-Naphthoquinono[3,2-c]-1H-pyrazoles,2-Substituted Amino-1,4-naphthoquinones, and Related Compounds</title><author>Tandon, V. K. ; Vaish, Meenu ; Khanna, J. M. ; Anand, Nitya</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4162-169f823f07d0ecaa191f8d2bbadbdf5ad881a9ee3a16a9685d843b6887a6330e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1990</creationdate><topic>Antineoplastic Agents - chemical synthesis</topic><topic>Bacteria - drug effects</topic><topic>Cells, Cultured</topic><topic>Chemical Phenomena</topic><topic>Chemistry</topic><topic>Exact sciences and technology</topic><topic>Fungi - drug effects</topic><topic>Heterocyclic compounds</topic><topic>Heterocyclic compounds with several n hetero atoms in the same ring, in separated rings or in fused rings</topic><topic>Naphthoquinones - chemical synthesis</topic><topic>Naphthoquinones - pharmacology</topic><topic>Organic chemistry</topic><topic>Preparations and properties</topic><topic>Pyrazoles - chemical synthesis</topic><topic>Pyrazoles - pharmacology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Tandon, V. K.</creatorcontrib><creatorcontrib>Vaish, Meenu</creatorcontrib><creatorcontrib>Khanna, J. M.</creatorcontrib><creatorcontrib>Anand, Nitya</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Archiv der Pharmazie (Weinheim)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Tandon, V. K.</au><au>Vaish, Meenu</au><au>Khanna, J. M.</au><au>Anand, Nitya</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Synthesis and Pharmacological Studies of Some (1,4)-Naphthoquinono[3,2-c]-1H-pyrazoles,2-Substituted Amino-1,4-naphthoquinones, and Related Compounds</atitle><jtitle>Archiv der Pharmazie (Weinheim)</jtitle><addtitle>Arch. Pharm. Pharm. Med. Chem</addtitle><date>1990</date><risdate>1990</risdate><volume>323</volume><issue>7</issue><spage>383</spage><epage>385</epage><pages>383-385</pages><issn>0365-6233</issn><eissn>1521-4184</eissn><coden>ARPMAS</coden><abstract>Series of (1,4)‐Naphthoquinono(3,2‐c)‐1H‐pyrazoles and 2‐substituted amino‐1,4‐naphthoquinones have been synthesised and studied for their possible anticancer activity (animal tumours, Walker 256 carcinosarcoma), Influenza RNA transcriptase activity, antibiotic activity (C. neoformans, T. mentagraphytes, M. canis, A. niger, and C. albicans).
Synthese und pharmakologische Prüfung einiger (1,4)‐Naphthochinon‐[3,2‐c]‐1H‐pyrazole, 2‐substituierter Amino‐1,4‐naphthochinone und verwandter Verbindungen
1,4‐Naphthochinon[3,2‐c]‐1H‐pyrazole and 2‐substituierte Amino‐1,4‐naphthochinone wurden hergestellt und auf cytostatische Wirkung (Tiertumore, Walker 256 Sarkom)), Influenza RNS‐Transkriptase Aktivität und antibiotische Wirksamkeit (C. neoformans, T. mentagraphytes, M. canis, A. niger und C. albicans) geprüft.</abstract><cop>Hannover</cop><pub>WILEY-VCH Verlag</pub><pmid>2241532</pmid><doi>10.1002/ardp.19903230702</doi><tpages>3</tpages></addata></record> |
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| ispartof | Archiv der Pharmazie (Weinheim), 1990, Vol.323 (7), p.383-385 |
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| language | eng |
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| source | MEDLINE; Wiley Online Library Journals Frontfile Complete |
| subjects | Antineoplastic Agents - chemical synthesis Bacteria - drug effects Cells, Cultured Chemical Phenomena Chemistry Exact sciences and technology Fungi - drug effects Heterocyclic compounds Heterocyclic compounds with several n hetero atoms in the same ring, in separated rings or in fused rings Naphthoquinones - chemical synthesis Naphthoquinones - pharmacology Organic chemistry Preparations and properties Pyrazoles - chemical synthesis Pyrazoles - pharmacology |
| title | Synthesis and Pharmacological Studies of Some (1,4)-Naphthoquinono[3,2-c]-1H-pyrazoles,2-Substituted Amino-1,4-naphthoquinones, and Related Compounds |
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