Royal jelly inhibits the production of proinflammatory cytokines by activated macrophages

In this study, we have examined the anti-inflammatory actions of royal jelly (RJ) at a cytokine level. When supernatants of RJ suspensions were added to a culture of mouse peritoneal macrophages stimulated with lipopolysaccharide and IFN-γ, the production of proinflammatory cytokines, such as TNF-α,...

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Veröffentlicht in:	Bioscience, biotechnology, and biochemistry biotechnology, and biochemistry, 2004-01, Vol.68 (1), p.138-145
Hauptverfasser:	Kohno, K. (Hayashibara Biochemical Labs. Inc., Okayama (Japan)), Okamoto, I, Sano, O, Arai, K, Ikeda, M, Kurimoto, M
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anti-Inflammatory Agents - pharmacology ANTIINFLAMMATORY AGENTS Biological and medical sciences Cells, Cultured CYTOKINES Cytokines - metabolism Fatty Acids - chemistry Fatty Acids - pharmacology Female Fundamental and applied biological sciences. Psychology Glycoproteins - chemistry Glycoproteins - pharmacology INFLAMMATION Inflammation - metabolism INHIBITION Insect Proteins - chemistry Insect Proteins - pharmacology Interferon-gamma - pharmacology Lipopolysaccharides - pharmacology macrophage Macrophage Activation - drug effects MACROPHAGES Macrophages, Peritoneal - drug effects Macrophages, Peritoneal - metabolism major royal jelly protein 3 (MRJP3) MICE Mice, Inbred BALB C MOLECULAR WEIGHT proinflammatory cytokine ROYAL JELLY royal jelly (RJ) Tumor Necrosis Factor-alpha - drug effects Tumor Necrosis Factor-alpha - metabolism
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