Measurement of antirotavirus IgM/IgA/IgG responses in the serum samples of Indian children following rotavirus diarrhoea and their mothers

Measurement of antirotavirus IgM/IgA/IgG responses in the serum samples of Indian children following rotavirus diarrhoea and their mothers

Rotavirus specific, serum IgM/IgA/IgG levels among hospitalized children and their respective mothers were determined. Children were grouped as having rotavirus diarrhoea (RVD) and non‐rotavirus diarrhoea (NRVD) on the basis of fecal excretion measured by ELISA and RT‐PCR. Although IgM seropositivit...

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Veröffentlicht in:Journal of medical virology 2004-03, Vol.72 (3), p.416-423
Hauptverfasser: Ray, Pratibha G., Kelkar, Shobhana D.
Format: Artikel
Sprache:eng
Schlagworte:
Adult
Antibodies, Viral - blood
Biological and medical sciences
Case-Control Studies
Diarrhea - immunology
Diarrhea - virology
Enzyme-Linked Immunosorbent Assay
Feces - virology
Female
Fundamental and applied biological sciences. Psychology
Human viral diseases
Humans
IgG
Immunoglobulin A - blood
Immunoglobulin G - blood
Immunoglobulin M - blood
India
Infant
Infectious diseases
isotypes responses
maternal
Medical sciences
Microbiology
Miscellaneous
Mothers
non-rotavirus diarrhoea
Reverse Transcriptase Polymerase Chain Reaction
Rotavirus
Rotavirus - immunology
Rotavirus - isolation & purification
rotavirus gastroenteritis
Rotavirus Infections - diagnosis
Rotavirus Infections - immunology
Rotavirus Infections - virology
Viral diseases
Virology
Virus Shedding
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Zusammenfassung:Rotavirus specific, serum IgM/IgA/IgG levels among hospitalized children and their respective mothers were determined. Children were grouped as having rotavirus diarrhoea (RVD) and non‐rotavirus diarrhoea (NRVD) on the basis of fecal excretion measured by ELISA and RT‐PCR. Although IgM seropositivity was observed among children of both the groups, it was significantly higher in the acute as well as convalescent phase serum samples (P 
ISSN:0146-6615
1096-9071
DOI:10.1002/jmv.20020