Binding of Sulfonylurea by AtMRP5, an Arabidopsis Multidrug Resistance-Related Protein That Functions in Salt Tolerance

Recently, a new member of the ABC transporter superfamily of Arabidopsis, AtMRP5, was identified and characterized. In the present work, we found that AtMRP5 can bind specifically to sulfonurea when it is expressed in HEK293 cells. We also present evidence for a new role of AtMRP5 in the salt stress...

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Veröffentlicht in:	Plant physiology (Bethesda) 2004-01, Vol.134 (1), p.528-538
Hauptverfasser:	Eun Kyung Lee, Minjae Kwon, Ko, Jae-Heung, Hochul Yi, Moo Gak Hwang, Soochul Chang, Myeon Haeng Cho
Format:	Artikel
Sprache:	eng
Schlagworte:	Arabidopsis - drug effects Arabidopsis - genetics Arabidopsis - metabolism Arabidopsis Proteins - genetics Arabidopsis Proteins - metabolism ATP binding cassette transporters Biological and medical sciences Cell Biology and Signal Transduction Cell Line Cell physiology DNA, Bacterial - genetics Fundamental and applied biological sciences. Psychology Gene Expression Gene expression regulation Genes, Plant Glyburide - metabolism Guard cells HEK293 cells Humans Ion Transport Mannitol - pharmacology Multidrug Resistance-Associated Proteins - genetics Multidrug Resistance-Associated Proteins - metabolism Mutation Plant cells Plant physiology and development Plants Plasma membrane and permeation Potassium - metabolism Protein Binding Recombinant Proteins - genetics Recombinant Proteins - metabolism Root growth Salt tolerance Seedlings Sodium Chloride - pharmacology Sulfonylurea Compounds - metabolism Transfection
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