Multivalent Mechanism of Membrane Insertion by the FYVE Domain

Targeting of a wide variety of proteins to membranes involves specific recognition of phospholipid head groups and insertion into lipid bilayers. For example, proteins that contain FYVE domains are recruited to endosomes through interaction with phosphatidylinositol 3-phosphate (PtdIns(3)P). However...

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Veröffentlicht in:	The Journal of biological chemistry 2004-01, Vol.279 (4), p.3050-3057
Hauptverfasser:	Kutateladze, Tatiana G., Capelluto, Daniel G.S., Ferguson, Colin G., Cheever, Matthew L., Kutateladze, Andrei G., Prestwich, Glenn D., Overduin, Michael
Format:	Artikel
Sprache:	eng
Schlagworte:	Binding Sites Cell Membrane - chemistry Cell Membrane - metabolism Humans Membrane Proteins - chemistry Membrane Proteins - metabolism Models, Molecular Protein Binding Protein Conformation Protein Structure, Tertiary Protein Transport Vesicular Transport Proteins
Online-Zugang:	Volltext
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