Transcriptional control of glial and blood cell development in Drosophila: cis-regulatory elements of glial cells missing

In Drosophila, glial cell differentiation requires the expression of glial cells missing ( gcm) in multiple neural cell lineages, where gcm acts as a binary switch for glial vs. neuronal fate. Thus, the primary event controlling gliogenesis in neural progenitors is the transcription of gcm. In addit...

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Veröffentlicht in:	Developmental biology 2004-02, Vol.266 (2), p.374-387
Hauptverfasser:	Jones, Bradley W, Abeysekera, Matthew, Galinska, Jolanta, Jolicoeur, Ethel M
Format:	Artikel
Sprache:	eng
Schlagworte:	abd-A Animals Animals, Genetically Modified Blood Cells - physiology Cell Differentiation - physiology Cell Lineage cis-regulatory elements CNS DNA-Binding Proteins Drosophila Drosophila melanogaster - anatomy & histology Drosophila melanogaster - embryology Drosophila melanogaster - genetics Drosophila melanogaster - physiology Drosophila Proteins Embryo, Nonmammalian - anatomy & histology Embryo, Nonmammalian - physiology gcm Gene Expression Regulation, Developmental Genes, Reporter germ cell missing gene Glia Hemocyte Homeotic genes In Situ Hybridization Macrophage Neuroglia - physiology Neuropeptides - genetics Neuropeptides - metabolism Regulatory Sequences, Nucleic Acid Trans-Activators - genetics Trans-Activators - metabolism Transcription Factors Transcription, Genetic
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