Hyperthermia Studies in Polyamine-Altered Human Lung Carcinoma Cells

The effect of polyamine depletion on the survival response of human lung carcinoma cells (A-549) to acute heating at 45°C and its effect on the induction and decay of thermotolerance were investigated in exponential and plateau-phase cells. A 48-h exposure to 1 mM α-difluoromethylornithine (DFMO), a...

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Veröffentlicht in:	Radiation research 1990-10, Vol.124 (1), p.S80-S87
Hauptverfasser:	Roizin-Towle, Laurie, Yarlett, Nigel, Pirro, John P., Delohery, Tom M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acclimatization - physiology Biological and medical sciences Cell cycle Cell Line Cell lines Cell Survival - drug effects CHO cells Cultured cells Effects of various physical factors on living matter (vibrations, electric field, ultrasound, sound...) Eflornithine - pharmacology Fundamental and applied biological sciences. Psychology Heat tolerance Hot Temperature Humans Hyperthermia In Vitro Techniques Lung Neoplasms Lungs Ornithine Decarboxylase Inhibitors Polyamines Polyamines - metabolism Shock heating Space life sciences Time Factors Tissues, organs and organisms biophysics Tumor Cells, Cultured - physiology Tumors
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