Evidence for a Second Interaction between the Regulatory Amino-terminal and Central Output Domains of the Response Regulator NtrC (Nitrogen Regulator I) in Escherichia coli

Nitrogen limitation in Escherichia coli activates about 100 genes. Their expression requires the response regulator NtrC (also called nitrogen regulator I or NRI). Phosphorylation of the amino-terminal domain (NTD) of NtrC activates the neighboring central domain and leads to transcriptional activat...

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Veröffentlicht in:	The Journal of biological chemistry 2004-01, Vol.279 (4), p.2350-2359
Hauptverfasser:	Harrod, Albert Carson, Yang, Xiaofeng, Junker, Matthew, Reitzer, Larry
Format:	Artikel
Sprache:	eng
Schlagworte:	Bacterial Proteins - chemistry Bacterial Proteins - metabolism DNA-Binding Proteins - chemistry DNA-Binding Proteins - metabolism Escherichia coli Escherichia coli - chemistry Escherichia coli - metabolism Escherichia coli Proteins Models, Molecular NtrC protein PII Nitrogen Regulatory Proteins Protein Conformation Protein Structure, Tertiary Signal Transduction Trans-Activators Transcription Factors
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