Five-Year results of 219 consecutive patients treated with extracorporeal membrane oxygenation for refractory postoperative cardiogenic shock
Postcardiotomy cardiogenic shock occurs in approximately 1% of patients. We prospectively evaluated the early and long-term outcome as well as predictors of survival when using temporary extracorporeal membrane oxygenation (ECMO) support. During 5 years 219 of 18,150 patients (1.2%) undergoing cardi...
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Veröffentlicht in: | The Annals of thoracic surgery 2004, Vol.77 (1), p.151-157 |
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creator | Doll, Nicolas Kiaii, Bob Borger, Michael Bucerius, Jan Krämer, Klaus Schmitt, Dierk V Walther, Thomas Mohr, Friedrich W |
description | Postcardiotomy cardiogenic shock occurs in approximately 1% of patients. We prospectively evaluated the early and long-term outcome as well as predictors of survival when using temporary extracorporeal membrane oxygenation (ECMO) support.
During 5 years 219 of 18,150 patients (1.2%) undergoing cardiac surgery (coronary artery bypass grafting, n = 119; aortic valve replacement, n = 24; coronary artery bypass grafting and aortic valve replacement, n = 21; coronary artery bypass grafting and mitral valve replacement , n = 11; other procedures, n = 44) required temporary postoperative ECMO support. The ECMO implantation was performed through the femoral vessels or through the right atrium and ascending aorta. Additional intraaortic balloon counterpulsation was employed in 144 patients to improve coronary blood flow.
Mean duration of ECMO support was 2.8 ± 2.2 days. One hundred thirty-four patients (60%) were successfully weaned from ECMO. Of these, 52 patients (24%) were discharged from the hospital after 29.9 ± 24 days. The main cause of death was myocardial failure. Five-year follow-up is 96% complete; 37 patients (74%) were alive with reasonable exercise capacity.
Extracorporeal membrane oxygenation is an acceptable technique for short-term treatment of refractory postoperative low cardiac output. It can save the lives of a group of very high risk patients. |
doi_str_mv | 10.1016/S0003-4975(03)01329-8 |
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During 5 years 219 of 18,150 patients (1.2%) undergoing cardiac surgery (coronary artery bypass grafting, n = 119; aortic valve replacement, n = 24; coronary artery bypass grafting and aortic valve replacement, n = 21; coronary artery bypass grafting and mitral valve replacement , n = 11; other procedures, n = 44) required temporary postoperative ECMO support. The ECMO implantation was performed through the femoral vessels or through the right atrium and ascending aorta. Additional intraaortic balloon counterpulsation was employed in 144 patients to improve coronary blood flow.
Mean duration of ECMO support was 2.8 ± 2.2 days. One hundred thirty-four patients (60%) were successfully weaned from ECMO. Of these, 52 patients (24%) were discharged from the hospital after 29.9 ± 24 days. The main cause of death was myocardial failure. Five-year follow-up is 96% complete; 37 patients (74%) were alive with reasonable exercise capacity.
Extracorporeal membrane oxygenation is an acceptable technique for short-term treatment of refractory postoperative low cardiac output. It can save the lives of a group of very high risk patients.</description><identifier>ISSN: 0003-4975</identifier><identifier>EISSN: 1552-6259</identifier><identifier>DOI: 10.1016/S0003-4975(03)01329-8</identifier><identifier>PMID: 14726052</identifier><language>eng</language><publisher>Netherlands: Elsevier Inc</publisher><subject>Aged ; Extracorporeal Membrane Oxygenation ; Female ; Humans ; Male ; Middle Aged ; Postoperative Complications - mortality ; Postoperative Complications - surgery ; Prognosis ; Prospective Studies ; Shock, Cardiogenic - mortality ; Shock, Cardiogenic - surgery ; Survival Rate ; Time Factors</subject><ispartof>The Annals of thoracic surgery, 2004, Vol.77 (1), p.151-157</ispartof><rights>2003 The Society of Thoracic Surgeons</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c396t-d57962c81c62cf7fae2529b6e627bb69c0a1db938df063f938935580078a35e13</citedby><cites>FETCH-LOGICAL-c396t-d57962c81c62cf7fae2529b6e627bb69c0a1db938df063f938935580078a35e13</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/S0003-4975(03)01329-8$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,4024,27923,27924,27925,45995</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/14726052$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Doll, Nicolas</creatorcontrib><creatorcontrib>Kiaii, Bob</creatorcontrib><creatorcontrib>Borger, Michael</creatorcontrib><creatorcontrib>Bucerius, Jan</creatorcontrib><creatorcontrib>Krämer, Klaus</creatorcontrib><creatorcontrib>Schmitt, Dierk V</creatorcontrib><creatorcontrib>Walther, Thomas</creatorcontrib><creatorcontrib>Mohr, Friedrich W</creatorcontrib><title>Five-Year results of 219 consecutive patients treated with extracorporeal membrane oxygenation for refractory postoperative cardiogenic shock</title><title>The Annals of thoracic surgery</title><addtitle>Ann Thorac Surg</addtitle><description>Postcardiotomy cardiogenic shock occurs in approximately 1% of patients. We prospectively evaluated the early and long-term outcome as well as predictors of survival when using temporary extracorporeal membrane oxygenation (ECMO) support.
During 5 years 219 of 18,150 patients (1.2%) undergoing cardiac surgery (coronary artery bypass grafting, n = 119; aortic valve replacement, n = 24; coronary artery bypass grafting and aortic valve replacement, n = 21; coronary artery bypass grafting and mitral valve replacement , n = 11; other procedures, n = 44) required temporary postoperative ECMO support. The ECMO implantation was performed through the femoral vessels or through the right atrium and ascending aorta. Additional intraaortic balloon counterpulsation was employed in 144 patients to improve coronary blood flow.
Mean duration of ECMO support was 2.8 ± 2.2 days. One hundred thirty-four patients (60%) were successfully weaned from ECMO. Of these, 52 patients (24%) were discharged from the hospital after 29.9 ± 24 days. The main cause of death was myocardial failure. Five-year follow-up is 96% complete; 37 patients (74%) were alive with reasonable exercise capacity.
Extracorporeal membrane oxygenation is an acceptable technique for short-term treatment of refractory postoperative low cardiac output. It can save the lives of a group of very high risk patients.</description><subject>Aged</subject><subject>Extracorporeal Membrane Oxygenation</subject><subject>Female</subject><subject>Humans</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Postoperative Complications - mortality</subject><subject>Postoperative Complications - surgery</subject><subject>Prognosis</subject><subject>Prospective Studies</subject><subject>Shock, Cardiogenic - mortality</subject><subject>Shock, Cardiogenic - surgery</subject><subject>Survival Rate</subject><subject>Time Factors</subject><issn>0003-4975</issn><issn>1552-6259</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2004</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkctu1TAQhq0K1J4WHoHKKwSLgC-1E69QVdGCVIkFZcHKcpwJdZvEqe2UnofgnTvnIliy8Xg83z_jmSHkDWcfOOP643fGmKzOTK3eMfmecSlM1RyQFVdKVFoo84Ks_iJH5DjnO3QFhg_JET-rhWZKrMify_AI1U9wiSbIy1AyjT0V3FAfpwx-KRinsysBJoyVBK5AR3-HckvhqSTnY5ojvg50hLFNbgIan9a_YEJJnGgfN4l75EpMazrHXOIMyW3Tepe6EJENnubb6O9fkZe9GzK83tsT8uPy883Fl-r629XXi_PrykujS9Wp2mjhG-7x7OvegVDCtBq0qNtWG88c71ojm65nWvZ4MVKphrG6cVIBlyfk7S7vnOLDArnYMWQPw4Dfj0u2DeNMCGYQVDvQp5gzNmLnFEaX1pYzu9mD3e7BboZs0W73YBvUne4LLO0I3T_VfvAIfNoBgG0-Bkg2exyxhy4k8MV2MfynxDPwOZr5</recordid><startdate>2004</startdate><enddate>2004</enddate><creator>Doll, Nicolas</creator><creator>Kiaii, Bob</creator><creator>Borger, Michael</creator><creator>Bucerius, Jan</creator><creator>Krämer, Klaus</creator><creator>Schmitt, Dierk V</creator><creator>Walther, Thomas</creator><creator>Mohr, Friedrich W</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>2004</creationdate><title>Five-Year results of 219 consecutive patients treated with extracorporeal membrane oxygenation for refractory postoperative cardiogenic shock</title><author>Doll, Nicolas ; Kiaii, Bob ; Borger, Michael ; Bucerius, Jan ; Krämer, Klaus ; Schmitt, Dierk V ; Walther, Thomas ; Mohr, Friedrich W</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c396t-d57962c81c62cf7fae2529b6e627bb69c0a1db938df063f938935580078a35e13</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2004</creationdate><topic>Aged</topic><topic>Extracorporeal Membrane Oxygenation</topic><topic>Female</topic><topic>Humans</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Postoperative Complications - mortality</topic><topic>Postoperative Complications - surgery</topic><topic>Prognosis</topic><topic>Prospective Studies</topic><topic>Shock, Cardiogenic - mortality</topic><topic>Shock, Cardiogenic - surgery</topic><topic>Survival Rate</topic><topic>Time Factors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Doll, Nicolas</creatorcontrib><creatorcontrib>Kiaii, Bob</creatorcontrib><creatorcontrib>Borger, Michael</creatorcontrib><creatorcontrib>Bucerius, Jan</creatorcontrib><creatorcontrib>Krämer, Klaus</creatorcontrib><creatorcontrib>Schmitt, Dierk V</creatorcontrib><creatorcontrib>Walther, Thomas</creatorcontrib><creatorcontrib>Mohr, Friedrich W</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>The Annals of thoracic surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Doll, Nicolas</au><au>Kiaii, Bob</au><au>Borger, Michael</au><au>Bucerius, Jan</au><au>Krämer, Klaus</au><au>Schmitt, Dierk V</au><au>Walther, Thomas</au><au>Mohr, Friedrich W</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Five-Year results of 219 consecutive patients treated with extracorporeal membrane oxygenation for refractory postoperative cardiogenic shock</atitle><jtitle>The Annals of thoracic surgery</jtitle><addtitle>Ann Thorac Surg</addtitle><date>2004</date><risdate>2004</risdate><volume>77</volume><issue>1</issue><spage>151</spage><epage>157</epage><pages>151-157</pages><issn>0003-4975</issn><eissn>1552-6259</eissn><abstract>Postcardiotomy cardiogenic shock occurs in approximately 1% of patients. We prospectively evaluated the early and long-term outcome as well as predictors of survival when using temporary extracorporeal membrane oxygenation (ECMO) support.
During 5 years 219 of 18,150 patients (1.2%) undergoing cardiac surgery (coronary artery bypass grafting, n = 119; aortic valve replacement, n = 24; coronary artery bypass grafting and aortic valve replacement, n = 21; coronary artery bypass grafting and mitral valve replacement , n = 11; other procedures, n = 44) required temporary postoperative ECMO support. The ECMO implantation was performed through the femoral vessels or through the right atrium and ascending aorta. Additional intraaortic balloon counterpulsation was employed in 144 patients to improve coronary blood flow.
Mean duration of ECMO support was 2.8 ± 2.2 days. One hundred thirty-four patients (60%) were successfully weaned from ECMO. Of these, 52 patients (24%) were discharged from the hospital after 29.9 ± 24 days. The main cause of death was myocardial failure. Five-year follow-up is 96% complete; 37 patients (74%) were alive with reasonable exercise capacity.
Extracorporeal membrane oxygenation is an acceptable technique for short-term treatment of refractory postoperative low cardiac output. It can save the lives of a group of very high risk patients.</abstract><cop>Netherlands</cop><pub>Elsevier Inc</pub><pmid>14726052</pmid><doi>10.1016/S0003-4975(03)01329-8</doi><tpages>7</tpages></addata></record> |
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subjects | Aged Extracorporeal Membrane Oxygenation Female Humans Male Middle Aged Postoperative Complications - mortality Postoperative Complications - surgery Prognosis Prospective Studies Shock, Cardiogenic - mortality Shock, Cardiogenic - surgery Survival Rate Time Factors |
title | Five-Year results of 219 consecutive patients treated with extracorporeal membrane oxygenation for refractory postoperative cardiogenic shock |
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