Aggressive or Expectant Management for Patients With Severe Preeclampsia Between 28–34 Weeksʼ Gestation: A Randomized Controlled Trial
Fifty-eight women with severe preeclampsia between 28-34 weeksʼ gestation qualified for a randomized controlled trial to establish whether elective delivery 48 hours after administration of betamethasone (aggressive-management group) or delivery later as indicated by maternal or fetal condition (exp...
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| Veröffentlicht in: | Obstetrics and gynecology (New York. 1953) 1990-12, Vol.76 (6), p.1070-1075 |
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| container_title | Obstetrics and gynecology (New York. 1953) |
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| creator | ODENDAAL, HEIN J PATTINSON, ROBERT C BAM, ROOSMARIE GROVE, DEBBIE KOTZE, THEUNIS J. v. W |
| description | Fifty-eight women with severe preeclampsia between 28-34 weeksʼ gestation qualified for a randomized controlled trial to establish whether elective delivery 48 hours after administration of betamethasone (aggressive-management group) or delivery later as indicated by maternal or fetal condition (expectant-management group) was more beneficial to maternal and fetal outcome. Twenty women who qualified were not randomized because they developed maternal or fetal indications necessitating delivery within 48 hours; these newborns developed most of the complications. Expectant management was not associated with an increase in maternal complications, but it significantly prolonged the gestational age (mean 7.1 days; P < .05), reduced the number of neonates requiring ventilation (P < .05), and reduced the number of neonatal complications (P < .05). |
| format | Article |
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W</creator><general>The American College of Obstetricians and Gynecologists</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>199012</creationdate><title>Aggressive or Expectant Management for Patients With Severe Preeclampsia Between 28–34 Weeksʼ Gestation: A Randomized Controlled Trial</title><author>ODENDAAL, HEIN J ; PATTINSON, ROBERT C ; BAM, ROOSMARIE ; GROVE, DEBBIE ; KOTZE, THEUNIS J. v. 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W</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Obstetrics and gynecology (New York. 1953)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>ODENDAAL, HEIN J</au><au>PATTINSON, ROBERT C</au><au>BAM, ROOSMARIE</au><au>GROVE, DEBBIE</au><au>KOTZE, THEUNIS J. v. 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Twenty women who qualified were not randomized because they developed maternal or fetal indications necessitating delivery within 48 hours; these newborns developed most of the complications. Expectant management was not associated with an increase in maternal complications, but it significantly prolonged the gestational age (mean 7.1 days; P < .05), reduced the number of neonates requiring ventilation (P < .05), and reduced the number of neonatal complications (P < .05).</abstract><cop>United States</cop><pub>The American College of Obstetricians and Gynecologists</pub><pmid>2234715</pmid><tpages>6</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0029-7844 |
| ispartof | Obstetrics and gynecology (New York. 1953), 1990-12, Vol.76 (6), p.1070-1075 |
| issn | 0029-7844 1873-233X |
| language | eng |
| recordid | cdi_proquest_miscellaneous_80101821 |
| source | MEDLINE; Journals@Ovid Complete |
| subjects | Betamethasone - therapeutic use Cesarean Section Female Gestational Age Humans Incidence Infant Mortality Infant, Newborn Infant, Newborn, Diseases - epidemiology Length of Stay Pre-Eclampsia - complications Pre-Eclampsia - therapy Pregnancy |
| title | Aggressive or Expectant Management for Patients With Severe Preeclampsia Between 28–34 Weeksʼ Gestation: A Randomized Controlled Trial |
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