Lipid metabolism in liver of chicks: response to feeding
Fatty-acid synthase is an enzyme complex responsible for the synthesis of the carbon chain of fatty acids. The hepatic activity of this enzyme increases rapidly during a refeeding period following a fast. The activity of fatty-acid synthase in liver of newly hatched chicks rises in parallel with the...
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| Veröffentlicht in: | Poultry science 1990-07, Vol.69 (7), p.1183-1187 |
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| container_title | Poultry science |
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| creator | Donaldson, W.E. (North Carolina State University, Raleigh, NC) |
| description | Fatty-acid synthase is an enzyme complex responsible for the synthesis of the carbon chain of fatty acids. The hepatic activity of this enzyme increases rapidly during a refeeding period following a fast. The activity of fatty-acid synthase in liver of newly hatched chicks rises in parallel with the activities of other lipogenic enzymes at the initiation of feeding. Cycloheximide, an inhibitor of protein synthesis, prevents the feeding-associated rise of other lipogenic enzymes, but not of fatty-acid synthase. Evidence is reviewed that supports the hypothesis that in fasted chicks as well as in unfed, newly hatched chicks, fatty-acid synthase exists in a catalytically less-active form, one that is activated in response to feeding. |
| doi_str_mv | 10.3382/ps.0691183 |
| format | Article |
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(North Carolina State University, Raleigh, NC)</creator><creatorcontrib>Donaldson, W.E. (North Carolina State University, Raleigh, NC)</creatorcontrib><description>Fatty-acid synthase is an enzyme complex responsible for the synthesis of the carbon chain of fatty acids. The hepatic activity of this enzyme increases rapidly during a refeeding period following a fast. The activity of fatty-acid synthase in liver of newly hatched chicks rises in parallel with the activities of other lipogenic enzymes at the initiation of feeding. Cycloheximide, an inhibitor of protein synthesis, prevents the feeding-associated rise of other lipogenic enzymes, but not of fatty-acid synthase. Evidence is reviewed that supports the hypothesis that in fasted chicks as well as in unfed, newly hatched chicks, fatty-acid synthase exists in a catalytically less-active form, one that is activated in response to feeding.</description><identifier>ISSN: 0032-5791</identifier><identifier>EISSN: 1525-3171</identifier><identifier>DOI: 10.3382/ps.0691183</identifier><identifier>PMID: 2235835</identifier><language>eng</language><publisher>England</publisher><subject>ACIDE GRAS ; ACIDOS GRASOS ; ALIMENTACION DE LOS ANIMALES ; ALIMENTATION DES ANIMAUX ; ANIMAL FEEDING ; Animals ; CARBOHIDRATOS ; CARBOHYDRATES ; Chickens - metabolism ; CHICKS ; Fasting ; Fatty Acid Synthases - metabolism ; FATTY ACIDS ; FOIE ; Food ; GLUCIDE ; GLUCOSA ; GLUCOSE ; HIGADO ; LIGASA ; LIGASE ; LIGASES ; LIPID METABOLISM ; LIVER ; Liver - enzymology ; Liver - metabolism ; METABOLISME DES LIPIDES ; METABOLISMO DE LIPIDOS ; POLLITO ; POUSSIN ; REGULATION ; SYNTHESIS</subject><ispartof>Poultry science, 1990-07, Vol.69 (7), p.1183-1187</ispartof><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c337t-62f6f72b5838991e00f03b829f70c3a6c25d3f932ef39b8be010bca6dfe308313</citedby><cites>FETCH-LOGICAL-c337t-62f6f72b5838991e00f03b829f70c3a6c25d3f932ef39b8be010bca6dfe308313</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/2235835$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Donaldson, W.E. (North Carolina State University, Raleigh, NC)</creatorcontrib><title>Lipid metabolism in liver of chicks: response to feeding</title><title>Poultry science</title><addtitle>Poult Sci</addtitle><description>Fatty-acid synthase is an enzyme complex responsible for the synthesis of the carbon chain of fatty acids. The hepatic activity of this enzyme increases rapidly during a refeeding period following a fast. The activity of fatty-acid synthase in liver of newly hatched chicks rises in parallel with the activities of other lipogenic enzymes at the initiation of feeding. Cycloheximide, an inhibitor of protein synthesis, prevents the feeding-associated rise of other lipogenic enzymes, but not of fatty-acid synthase. Evidence is reviewed that supports the hypothesis that in fasted chicks as well as in unfed, newly hatched chicks, fatty-acid synthase exists in a catalytically less-active form, one that is activated in response to feeding.</description><subject>ACIDE GRAS</subject><subject>ACIDOS GRASOS</subject><subject>ALIMENTACION DE LOS ANIMALES</subject><subject>ALIMENTATION DES ANIMAUX</subject><subject>ANIMAL FEEDING</subject><subject>Animals</subject><subject>CARBOHIDRATOS</subject><subject>CARBOHYDRATES</subject><subject>Chickens - metabolism</subject><subject>CHICKS</subject><subject>Fasting</subject><subject>Fatty Acid Synthases - metabolism</subject><subject>FATTY ACIDS</subject><subject>FOIE</subject><subject>Food</subject><subject>GLUCIDE</subject><subject>GLUCOSA</subject><subject>GLUCOSE</subject><subject>HIGADO</subject><subject>LIGASA</subject><subject>LIGASE</subject><subject>LIGASES</subject><subject>LIPID METABOLISM</subject><subject>LIVER</subject><subject>Liver - enzymology</subject><subject>Liver - metabolism</subject><subject>METABOLISME DES LIPIDES</subject><subject>METABOLISMO DE LIPIDOS</subject><subject>POLLITO</subject><subject>POUSSIN</subject><subject>REGULATION</subject><subject>SYNTHESIS</subject><issn>0032-5791</issn><issn>1525-3171</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1990</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo9kD1PwzAQhi0EKqWwMCIhZWJASrF9jWOzoYovqRIDdLYc51wMSRzsFIl_T1Arphve597TPYScMzoHkPymT3MqFGMSDsiUFbzIgZXskEwpBZ4XpWLH5CSlD0o5E6KckAnnUEgopkSufO_rrMXBVKHxqc18lzX-G2MWXGbfvf1Mt1nE1IcuYTaEzCHWvtuckiNnmoRn-zkj64f7t-VTvnp5fF7erXILUA654E64klfjNakUQ0odhUpy5UpqwQjLixqcAo4OVCUrpIxW1ojaIVAJDGbkatfbx_C1xTTo1ieLTWM6DNuk5bgwPvsHXu9AG0NKEZ3uo29N_NGM6j9Nuk96r2mEL_et26rF-h_dexnzi13uTNBmE33S61dFF3KhBPwCsa9pRg</recordid><startdate>19900701</startdate><enddate>19900701</enddate><creator>Donaldson, W.E. (North Carolina State University, Raleigh, NC)</creator><scope>FBQ</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19900701</creationdate><title>Lipid metabolism in liver of chicks: response to feeding</title><author>Donaldson, W.E. (North Carolina State University, Raleigh, NC)</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c337t-62f6f72b5838991e00f03b829f70c3a6c25d3f932ef39b8be010bca6dfe308313</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1990</creationdate><topic>ACIDE GRAS</topic><topic>ACIDOS GRASOS</topic><topic>ALIMENTACION DE LOS ANIMALES</topic><topic>ALIMENTATION DES ANIMAUX</topic><topic>ANIMAL FEEDING</topic><topic>Animals</topic><topic>CARBOHIDRATOS</topic><topic>CARBOHYDRATES</topic><topic>Chickens - metabolism</topic><topic>CHICKS</topic><topic>Fasting</topic><topic>Fatty Acid Synthases - metabolism</topic><topic>FATTY ACIDS</topic><topic>FOIE</topic><topic>Food</topic><topic>GLUCIDE</topic><topic>GLUCOSA</topic><topic>GLUCOSE</topic><topic>HIGADO</topic><topic>LIGASA</topic><topic>LIGASE</topic><topic>LIGASES</topic><topic>LIPID METABOLISM</topic><topic>LIVER</topic><topic>Liver - enzymology</topic><topic>Liver - metabolism</topic><topic>METABOLISME DES LIPIDES</topic><topic>METABOLISMO DE LIPIDOS</topic><topic>POLLITO</topic><topic>POUSSIN</topic><topic>REGULATION</topic><topic>SYNTHESIS</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Donaldson, W.E. (North Carolina State University, Raleigh, NC)</creatorcontrib><collection>AGRIS</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Poultry science</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Donaldson, W.E. (North Carolina State University, Raleigh, NC)</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Lipid metabolism in liver of chicks: response to feeding</atitle><jtitle>Poultry science</jtitle><addtitle>Poult Sci</addtitle><date>1990-07-01</date><risdate>1990</risdate><volume>69</volume><issue>7</issue><spage>1183</spage><epage>1187</epage><pages>1183-1187</pages><issn>0032-5791</issn><eissn>1525-3171</eissn><abstract>Fatty-acid synthase is an enzyme complex responsible for the synthesis of the carbon chain of fatty acids. The hepatic activity of this enzyme increases rapidly during a refeeding period following a fast. The activity of fatty-acid synthase in liver of newly hatched chicks rises in parallel with the activities of other lipogenic enzymes at the initiation of feeding. Cycloheximide, an inhibitor of protein synthesis, prevents the feeding-associated rise of other lipogenic enzymes, but not of fatty-acid synthase. Evidence is reviewed that supports the hypothesis that in fasted chicks as well as in unfed, newly hatched chicks, fatty-acid synthase exists in a catalytically less-active form, one that is activated in response to feeding.</abstract><cop>England</cop><pmid>2235835</pmid><doi>10.3382/ps.0691183</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0032-5791 |
| ispartof | Poultry science, 1990-07, Vol.69 (7), p.1183-1187 |
| issn | 0032-5791 1525-3171 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_80101711 |
| source | Electronic Journals Library; MEDLINE; Alma/SFX Local Collection |
| subjects | ACIDE GRAS ACIDOS GRASOS ALIMENTACION DE LOS ANIMALES ALIMENTATION DES ANIMAUX ANIMAL FEEDING Animals CARBOHIDRATOS CARBOHYDRATES Chickens - metabolism CHICKS Fasting Fatty Acid Synthases - metabolism FATTY ACIDS FOIE Food GLUCIDE GLUCOSA GLUCOSE HIGADO LIGASA LIGASE LIGASES LIPID METABOLISM LIVER Liver - enzymology Liver - metabolism METABOLISME DES LIPIDES METABOLISMO DE LIPIDOS POLLITO POUSSIN REGULATION SYNTHESIS |
| title | Lipid metabolism in liver of chicks: response to feeding |
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