Calcineurin signaling and NFAT activation in cardiovascular and skeletal muscle development

Calcineurin signaling has been implicated in a broad spectrum of developmental processes in a variety of organ systems. Calcineurin is a calmodulin-dependent, calcium-activated protein phosphatase composed of catalytic and regulatory subunits. The serine/threonine-specific phosphatase functions with...

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Veröffentlicht in:	Developmental Biology 2004-02, Vol.266 (1), p.1-16
Hauptverfasser:	Schulz, Robert A, Yutzey, Katherine E
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals C. elegans Caenorhabditis elegans Calcineurin Calcineurin - metabolism Cardiomyocyte Cardiovascular System - cytology Cardiovascular System - growth & development Cell Differentiation DNA-Binding Proteins - metabolism Drosophila Fiber-type specialization Humans Hypertrophy Indirect flight muscle Interacting genes Muscle, Skeletal - cytology Muscle, Skeletal - growth & development NFAT NFATC Transcription Factors Nuclear Proteins Signal Transduction Skeletal muscle Transcription Factors - metabolism Valvuloseptal development Vascular development
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