Effect of Helicobacter pylori eradication on high-density lipoprotein cholesterol
We examined the effect of Helicobacter pylori ( H. pylori) eradication on lipids and apolipoproteins in 87 patients with duodenal ulcers. A significant increase was observed in high-density lipoprotein (HDL) cholesterol (+24.7%, p
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Veröffentlicht in: | The American journal of cardiology 2004-01, Vol.93 (2), p.219-220 |
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container_title | The American journal of cardiology |
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creator | Scharnagl, Hubert Kist, Manfred Grawitz, Andrea Busse Koenig, Wolfgang Wieland, Heinrich März, Winfried |
description | We examined the effect of
Helicobacter pylori (
H. pylori) eradication on lipids and apolipoproteins in 87 patients with duodenal ulcers. A significant increase was observed in high-density lipoprotein (HDL) cholesterol (+24.7%, p |
doi_str_mv | 10.1016/j.amjcard.2003.09.045 |
format | Article |
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Helicobacter pylori (
H. pylori) eradication on lipids and apolipoproteins in 87 patients with duodenal ulcers. A significant increase was observed in high-density lipoprotein (HDL) cholesterol (+24.7%, p <0.001), apolipoprotein AI (+9.0%, p <0.001), and apolipoprotein AII (+11.7%, p <0.001) after eradication. Minor increases occurred in total cholesterol, triglycerides, and apolipoprotein B, whereas low-density lipoprotein cholesterol remained unchanged. Our results suggest that chronic
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Helicobacter pylori (
H. pylori) eradication on lipids and apolipoproteins in 87 patients with duodenal ulcers. A significant increase was observed in high-density lipoprotein (HDL) cholesterol (+24.7%, p <0.001), apolipoprotein AI (+9.0%, p <0.001), and apolipoprotein AII (+11.7%, p <0.001) after eradication. Minor increases occurred in total cholesterol, triglycerides, and apolipoprotein B, whereas low-density lipoprotein cholesterol remained unchanged. Our results suggest that chronic
H. pylori infection reduces plasma levels of HDL cholesterol and that eradication improves the lipoprotein pattern.</description><subject>Apolipoprotein A-I - blood</subject><subject>Apolipoprotein A-II - blood</subject><subject>Apolipoproteins B - blood</subject><subject>Biological and medical sciences</subject><subject>Cardiology. Vascular system</subject><subject>Cholesterol, HDL - blood</subject><subject>Coronary Disease - epidemiology</subject><subject>Drug Therapy, Combination</subject><subject>Duodenal Ulcer - blood</subject><subject>Duodenal Ulcer - microbiology</subject><subject>Female</subject><subject>Heart</subject><subject>Helicobacter Infections - blood</subject><subject>Helicobacter Infections - drug therapy</subject><subject>Helicobacter pylori - isolation & purification</subject><subject>Humans</subject><subject>Lipoproteins - blood</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Retrospective Studies</subject><subject>Risk</subject><subject>Triglycerides - blood</subject><issn>0002-9149</issn><issn>1879-1913</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2004</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkMFqGzEQhkVoiN20j9Cyl-a225G02rVOpYSkDhhKIDkLSTuqZeSVK60LfvsqeMHHgGAQfP_Mz0fIFwoNBdp93zV6v7M6DQ0D4A3IBlpxRZZ01cuaSso_kCUAsFrSVi7Ix5x35Uup6G7IgrY9FVzwJXl-cA7tVEVXrTF4G422E6bqcAox-QqTHrzVk49jVd7W_9nWA47ZT6cq-EM8pDihHyu7jQFzCcbwiVw7HTJ-nucteX18eLlf15vfv57uf25q24p-qo3hWgzOINO87wyDTmjNetmBoRRN6Ykt76xwgsuhd9gxyZizhlnkTPKO35K7897S4e-xHFd7ny2GoEeMx6xWAJIL6AsozqBNMeeETh2S3-t0UhTUm0u1U7NL9eZSgVTFZcl9nQ8czR6HS2qWV4BvM6Cz1cElPVqfL5zoOYdVW7gfZw6Ljn8ek8rW42hx8Km4V0P071T5D9_3la4</recordid><startdate>20040115</startdate><enddate>20040115</enddate><creator>Scharnagl, Hubert</creator><creator>Kist, Manfred</creator><creator>Grawitz, Andrea Busse</creator><creator>Koenig, Wolfgang</creator><creator>Wieland, Heinrich</creator><creator>März, Winfried</creator><general>Elsevier Inc</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20040115</creationdate><title>Effect of Helicobacter pylori eradication on high-density lipoprotein cholesterol</title><author>Scharnagl, Hubert ; Kist, Manfred ; Grawitz, Andrea Busse ; Koenig, Wolfgang ; Wieland, Heinrich ; März, Winfried</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c457t-bb3a5dfbe2a376b2065aa27960b11eb156e436c5f539d7fe62922fcb2ce329363</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2004</creationdate><topic>Apolipoprotein A-I - blood</topic><topic>Apolipoprotein A-II - blood</topic><topic>Apolipoproteins B - blood</topic><topic>Biological and medical sciences</topic><topic>Cardiology. Vascular system</topic><topic>Cholesterol, HDL - blood</topic><topic>Coronary Disease - epidemiology</topic><topic>Drug Therapy, Combination</topic><topic>Duodenal Ulcer - blood</topic><topic>Duodenal Ulcer - microbiology</topic><topic>Female</topic><topic>Heart</topic><topic>Helicobacter Infections - blood</topic><topic>Helicobacter Infections - drug therapy</topic><topic>Helicobacter pylori - isolation & purification</topic><topic>Humans</topic><topic>Lipoproteins - blood</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Retrospective Studies</topic><topic>Risk</topic><topic>Triglycerides - blood</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Scharnagl, Hubert</creatorcontrib><creatorcontrib>Kist, Manfred</creatorcontrib><creatorcontrib>Grawitz, Andrea Busse</creatorcontrib><creatorcontrib>Koenig, Wolfgang</creatorcontrib><creatorcontrib>Wieland, Heinrich</creatorcontrib><creatorcontrib>März, Winfried</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>The American journal of cardiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Scharnagl, Hubert</au><au>Kist, Manfred</au><au>Grawitz, Andrea Busse</au><au>Koenig, Wolfgang</au><au>Wieland, Heinrich</au><au>März, Winfried</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Effect of Helicobacter pylori eradication on high-density lipoprotein cholesterol</atitle><jtitle>The American journal of cardiology</jtitle><addtitle>Am J Cardiol</addtitle><date>2004-01-15</date><risdate>2004</risdate><volume>93</volume><issue>2</issue><spage>219</spage><epage>220</epage><pages>219-220</pages><issn>0002-9149</issn><eissn>1879-1913</eissn><coden>AJCDAG</coden><abstract>We examined the effect of
Helicobacter pylori (
H. pylori) eradication on lipids and apolipoproteins in 87 patients with duodenal ulcers. A significant increase was observed in high-density lipoprotein (HDL) cholesterol (+24.7%, p <0.001), apolipoprotein AI (+9.0%, p <0.001), and apolipoprotein AII (+11.7%, p <0.001) after eradication. Minor increases occurred in total cholesterol, triglycerides, and apolipoprotein B, whereas low-density lipoprotein cholesterol remained unchanged. Our results suggest that chronic
H. pylori infection reduces plasma levels of HDL cholesterol and that eradication improves the lipoprotein pattern.</abstract><cop>New York, NY</cop><pub>Elsevier Inc</pub><pmid>14715353</pmid><doi>10.1016/j.amjcard.2003.09.045</doi><tpages>2</tpages></addata></record> |
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subjects | Apolipoprotein A-I - blood Apolipoprotein A-II - blood Apolipoproteins B - blood Biological and medical sciences Cardiology. Vascular system Cholesterol, HDL - blood Coronary Disease - epidemiology Drug Therapy, Combination Duodenal Ulcer - blood Duodenal Ulcer - microbiology Female Heart Helicobacter Infections - blood Helicobacter Infections - drug therapy Helicobacter pylori - isolation & purification Humans Lipoproteins - blood Male Medical sciences Middle Aged Retrospective Studies Risk Triglycerides - blood |
title | Effect of Helicobacter pylori eradication on high-density lipoprotein cholesterol |
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