Regulation of systolic force and control of free energy of ATP-hydrolysis in hypoxic hearts

In isolated isometrically working rat hearts during graded, constant pressure hypoxic saline perfusion ( P o 2 140–700 mmHg) heart rate was changed experimentally between 80 and 400/min. The following parameters were recorded or estimated: peak systolic pressure, dP dt max , dP t min , oxygen consum...

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Veröffentlicht in:	Journal of molecular and cellular cardiology 1990-06, Vol.22 (6), p.707-713
Hauptverfasser:	Kammermeier, H., Roeb, E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Triphosphate - metabolism Animals Biological and medical sciences Energy Metabolism - physiology Female Force-frequency relationship Free energy of ATP Fundamental and applied biological sciences. Psychology Heart Heart - physiology Hydrolysis Hypoxia Hypoxia - metabolism Hypoxia - physiopathology Inorganic P Myocardial Contraction - physiology Myocardium - metabolism Oxygen Consumption - physiology Rats Rats, Inbred Strains Space life sciences Systole - physiology Vertebrates: cardiovascular system
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