Adenovirus Gene Transfer of Recombinant Endothelial Nitric Oxide Synthase Enhances Contractile Function in Ventricular Myocytes

eNOS is expressed in cardiac myocytes and plays an important role in cardiac contractile function. This study was designed to determine whether ex vivo eNOS gene transfer in ventricular myocytes affects cardiac contractile function. Replication-incompetent adenoviral vectors encoding eNOS or marker...

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Veröffentlicht in:	Journal of cardiovascular pharmacology 2004-02, Vol.43 (2), p.171-177
Hauptverfasser:	Ren, Jun, Zhang, Xiaochun, Scott, Glenda I, Esberg, Lucy B, Ren, Bonnie H, Culver, Bruce, Chen, Alex F
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenoviridae - genetics Animals Blotting, Western Calcium - metabolism Gene Transfer Techniques Male Myocardial Contraction - physiology Myocytes, Cardiac - metabolism Nitric Oxide Synthase - genetics Nitric Oxide Synthase - metabolism Nitric Oxide Synthase - physiology Phosphorylation Rats Rats, Sprague-Dawley
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