Forced lytic replication impairs host colonization by a latency-deficient mutant of murine gammaherpesvirus-68

Division of Virology, Department of Pathology, University of Cambridge, Tennis Court Road, Cambridge CB2 1QP, UK Correspondence Philip Stevenson pgs27{at}mole.bio.cam.ac.uk A regulated switch between latent and lytic gene expression is common to all known herpesviruses. However, the effects on host...

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Veröffentlicht in:	Journal of general virology 2004-01, Vol.85 (1), p.137-146
Hauptverfasser:	May, Janet S, Coleman, Heather M, Smillie, Belinda, Efstathiou, Stacey, Stevenson, Philip G
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Base Sequence Biological and medical sciences Cell Line Cricetinae Female Fundamental and applied biological sciences. Psychology Gammaherpesvirinae - genetics Gammaherpesvirinae - growth & development Gammaherpesvirinae - pathogenicity Gammaherpesvirinae - physiology Gene Expression Regulation, Viral Herpesviridae Infections - virology Mice Mice, Inbred C57BL Microbiology Miscellaneous Molecular Sequence Data Murine gammaherpesvirus 68 Mutation NIH 3T3 Cells Open Reading Frames - genetics Viral Proteins - genetics Virology Virulence Virus Activation Virus Latency - genetics Virus Replication
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