Expression of tissue factor mRNA and invasion of blood vessels by tumor cells in non-small cell lung cancer

Tissue factor (TF), an initiator of the extrinsic coagulation cascade, is also expressed in a wide range of cancer cells and plays an important role in cancer progression and metastasis, as well as in processes independent of the blood coagulation pathway. For example, by acting as an adhesion molec...

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Veröffentlicht in:	Surgery today (Tokyo, Japan) Japan), 2004, Vol.34 (1), p.1-5
Hauptverfasser:	Minamiya, Yoshihiro, Matsuzaki, Ikuo, Sageshima, Masato, Saito, Hajime, Taguchi, Kousei, Nakagawa, Taku, Ogawa, Jun-ichi
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Analysis of Variance Biomarkers, Tumor - metabolism Carcinoma, Non-Small-Cell Lung - pathology Female Humans Lung Neoplasms - pathology Lymphatic Metastasis - pathology Male Middle Aged Neoplasm Invasiveness - pathology Neovascularization, Pathologic Reverse Transcriptase Polymerase Chain Reaction RNA, Messenger - metabolism RNA, Neoplasm - metabolism Thromboplastin - metabolism
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