Enhancement of apparent substrate selectivity of proteinase K encapsulated in liposomes through a cholate-induced alteration of the bilayer permeability

Proteinase K‐containing liposomes with highly selective membrane permeability properties were prepared. The selectivity obtained was with respect to the two substrate molecules added to the external aqueous phase of the liposomes: acetyl‐L‐Ala‐Ala‐Ala‐p‐nitroanilide (Ac‐AAA‐pNA) and succinyl‐L‐Ala‐A...

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