Fluid mechanics of a spinner-flask bioreactor

Spinner‐flask bioreactors have been used for the production of articular cartilage in vitro. The dynamic environment within bioreactors is known to significantly affect the growth and development of the tissue. The present research focuses on the experimental and numerical characterization of the fl...

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Veröffentlicht in:	Biotechnology and bioengineering 2004-01, Vol.85 (1), p.34-46
Hauptverfasser:	Sucosky, Philippe, Osorio, Diego F., Brown, Jason B., Neitzel, G. Paul
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Bioreactors Biotechnology cartilage Cartilage - growth & development Cell Culture Techniques - instrumentation Cell Culture Techniques - methods computational fluid dynamics Computer Simulation Equipment Failure Analysis - instrumentation Equipment Failure Analysis - methods Fundamental and applied biological sciences. Psychology Methods. Procedures. Technologies Models, Theoretical Motion particle-image velocimetry Pilot Projects porous media Pressure Rheology - instrumentation Rheology - methods Rotation spinner-flask bioreactor Stress, Mechanical tissue engineering Tissue Engineering - instrumentation Tissue Engineering - methods Various methods and equipments
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