Renin-angiotensin system as a therapeutic target in managing atherosclerosis

Clinical and experimental evidence suggests that the pathways by which hypertension and dyslipidemia lead to vascular disease may overlap and that angiotensin II (Ang II) is involved in restructuring of the arterial wall in both atherosclerosis and hypertension. Ang II represents a potent proinflamm...

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Veröffentlicht in:	American journal of therapeutics 2004-01, Vol.11 (1), p.44-53
Hauptverfasser:	Ferrario, Carlos M, Richmond, Renee S, Smith, Ronald, Levy, Pavel, Strawn, William B, Kivlighn, Salah
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiotensin II - physiology Angiotensin Receptor Antagonists Arteriosclerosis - drug therapy Arteriosclerosis - etiology Arteriosclerosis - prevention & control Drug Therapy, Combination Humans Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use Hyperlipidemias - complications Hyperlipidemias - drug therapy Hyperlipidemias - pathology Hypertension - complications Renin-Angiotensin System - drug effects Renin-Angiotensin System - physiology
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