Automatic geometrical registration of fluorescein retinal angiograms

Changes in retinal microvascular perfusion revealed by fluorescein angiography have been reported in patients undergoing coronary artery surgery. Quantification of these changes is important and current techniques depend on careful visual inspection of the angiograms by humans. Computer image proces...

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Veröffentlicht in:Computers and biomedical research 1990-10, Vol.23 (5), p.403-409
Hauptverfasser: Jagoe, Roger, Blauth, Christopher I., Smith, Peter L., Arnold, John V., Taylor, Kenneth, Wootton, Richard
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container_issue 5
container_start_page 403
container_title Computers and biomedical research
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creator Jagoe, Roger
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Arnold, John V.
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Wootton, Richard
description Changes in retinal microvascular perfusion revealed by fluorescein angiography have been reported in patients undergoing coronary artery surgery. Quantification of these changes is important and current techniques depend on careful visual inspection of the angiograms by humans. Computer image processing methods can be used to identify and highlight differences, but geometrical registration of the images is a prerequisite to the comparisons. Automatic methods for locating and matching reference points have therefore been developed. In combination with an iterative process which used least-squares error to calculate the transformation coefficients, subsets of reference points were selected and used to register successfully 20 image pairs.
doi_str_mv 10.1016/0010-4809(90)90030-G
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subjects Biological and medical sciences
Coronary Artery Bypass - methods
Fluorescein Angiography - methods
Humans
Image Processing, Computer-Assisted
Investigative techniques, diagnostic techniques (general aspects)
Mathematical Computing
Medical sciences
Miscellaneous. Technology
Radiodiagnosis. Nmr imagery. Nmr spectrometry
Radiography
Retinal Vessels - diagnostic imaging
title Automatic geometrical registration of fluorescein retinal angiograms
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