Involvement of BAFF and APRIL in the resistance to apoptosis of B-CLL through an autocrine pathway

Tumor necrosis factor (TNF) superfamily members BAFF, or B-cell activation factor of the TNF family, and APRIL, a proliferation-inducing ligand, are involved in normal B-cell survival and differentiation. They interact with 3 receptors: BAFF-R, specific to BAFF; and TACI and BCMA, which are shared b...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Blood 2004-01, Vol.103 (2), p.679-688
Hauptverfasser:	Kern, Catherine, Cornuel, Jean-François, Billard, Christian, Tang, Ruoping, Rouillard, Danielle, Stenou, Virginie, Defrance, Thierry, Ajchenbaum-Cymbalista, Florence, Simonin, Pierre-Yves, Feldblum, Sophie, Kolb, Jean-Pierre
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Antibodies Apoptosis B-Cell Activating Factor Base Sequence Biological and medical sciences DNA Primers Female Flow Cytometry Gene Expression Regulation, Neoplastic - genetics Hematologic and hematopoietic diseases Humans Leukemia, Lymphocytic, Chronic, B-Cell - blood Leukemia, Lymphocytic, Chronic, B-Cell - genetics Leukemia, Lymphocytic, Chronic, B-Cell - pathology Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis Male Mass Spectrometry Medical sciences Membrane Proteins - blood Membrane Proteins - genetics Membrane Proteins - immunology Middle Aged Neoplasm Staging Neuropeptides - blood Neuropeptides - genetics Neuropeptides - immunology NF-kappa B - metabolism Nuclear Proteins Nucleosomes - genetics Receptors, Tumor Necrosis Factor - genetics Reverse Transcriptase Polymerase Chain Reaction RNA, Messenger - genetics Tumor Necrosis Factor Ligand Superfamily Member 13 Tumor Necrosis Factor-alpha - genetics Tumor Necrosis Factor-alpha - immunology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!