Neuropsychological correlates of psychotic features in major depressive disorders: a review and meta-analysis
Neuropsychological functioning has been a focus of study in psychotic disorders for many decades. These studies have focused primarily on schizophrenia, and less so on the affective psychoses, including psychotic major depression PMD. Several studies have provided evidence of cognitive dysfunction i...
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| Veröffentlicht in: | Journal of psychiatric research 2004, Vol.38 (1), p.27-35 |
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| container_title | Journal of psychiatric research |
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| creator | Fleming, Shelley K. Blasey, Christine Schatzberg, Alan F. |
| description | Neuropsychological functioning has been a focus of study in psychotic disorders for many decades. These studies have focused primarily on schizophrenia, and less so on the affective psychoses, including psychotic major depression PMD. Several studies have provided evidence of cognitive dysfunction in PMD. However, these studies have utilized different assessment methods and instruments. Consequently, a clear picture of the nature and severity of cognitive impairment in PMD has yet to emerge in the literature. The current review seeks to provide a summary of the literature by composing a quantitative and qualitative review of the research to date on the cognitive impairment in psychotic major depression, specifically as it contrasts to those deficits observed in nonpsychotic depression. This review also provides a summary model of the pathophysiology of PMD to provide the necessary context to understanding the biological mechanisms of these impairments. |
| doi_str_mv | 10.1016/S0022-3956(03)00100-6 |
| format | Article |
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These studies have focused primarily on schizophrenia, and less so on the affective psychoses, including psychotic major depression PMD. Several studies have provided evidence of cognitive dysfunction in PMD. However, these studies have utilized different assessment methods and instruments. Consequently, a clear picture of the nature and severity of cognitive impairment in PMD has yet to emerge in the literature. The current review seeks to provide a summary of the literature by composing a quantitative and qualitative review of the research to date on the cognitive impairment in psychotic major depression, specifically as it contrasts to those deficits observed in nonpsychotic depression. This review also provides a summary model of the pathophysiology of PMD to provide the necessary context to understanding the biological mechanisms of these impairments.</description><subject>Adult and adolescent clinical studies</subject><subject>Affective Disorders, Psychotic - diagnosis</subject><subject>Affective Disorders, Psychotic - psychology</subject><subject>Biological and medical sciences</subject><subject>Cognition Disorders - diagnosis</subject><subject>Cognition Disorders - psychology</subject><subject>Cognitive</subject><subject>Cortisol</subject><subject>Depression</subject><subject>Depressive Disorder, Major - diagnosis</subject><subject>Depressive Disorder, Major - psychology</subject><subject>Diagnosis, Differential</subject><subject>Humans</subject><subject>Medical sciences</subject><subject>Mood disorders</subject><subject>Neuropsychological Tests - statistics & numerical data</subject><subject>Neuropsychology</subject><subject>Other psychotic disorders</subject><subject>Psychology. 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Psychiatry</subject><subject>Psychoses</subject><subject>Psychotic</subject><subject>Schizophrenia - diagnosis</subject><subject>Schizophrenic Psychology</subject><issn>0022-3956</issn><issn>1879-1379</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2004</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkEtv1DAQgC1ERZfCTwD5AoJDwI6f6QWhCihSBQfgbE2cMbhK4sVOWu2_x9td0WNPo5n55qGPkBecveOM6_c_GGvbRnRKv2HiLWOcsUY_IhtuTddwYbrHZPMfOSVPS7lmjJmWyyfklEvdMaPthkzfcM1pW3b-TxrT7-hhpD7ljCMsWGgK9NBboqcBYVlzrcaZTnCdMh1wW_MSb5AOsaQ8YC7nFGjGm4i3FOaBTrhAAzOMuxLLM3ISYCz4_BjPyK_Pn35eXDZX3798vfh41XjF5NIIbYRG3_c9DEHZIFvFZfBWiF5xa0GaHlRvQfigOqtRtAhSgfVKGGORiTPy-rB3m9PfFcviplg8jiPMmNbibDVhpDUVVAfQ51RKxuC2OU6Qd44zt_fs7jy7vUTHhLvz7HSde3k8sPYTDvdTR7EVeHUEoFSnIcPsY7nnlOSik_sHPhw4rDqqtOyKjzh7HGJGv7ghxQde-QdOq5wZ</recordid><startdate>2004</startdate><enddate>2004</enddate><creator>Fleming, Shelley K.</creator><creator>Blasey, Christine</creator><creator>Schatzberg, Alan F.</creator><general>Elsevier Ltd</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>2004</creationdate><title>Neuropsychological correlates of psychotic features in major depressive disorders: a review and meta-analysis</title><author>Fleming, Shelley K. ; Blasey, Christine ; Schatzberg, Alan F.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c504t-36736ecbbbadf58f42514fc833b5188a47ba5b8a3cf5986e32ea45a8c53778e03</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2004</creationdate><topic>Adult and adolescent clinical studies</topic><topic>Affective Disorders, Psychotic - diagnosis</topic><topic>Affective Disorders, Psychotic - psychology</topic><topic>Biological and medical sciences</topic><topic>Cognition Disorders - diagnosis</topic><topic>Cognition Disorders - psychology</topic><topic>Cognitive</topic><topic>Cortisol</topic><topic>Depression</topic><topic>Depressive Disorder, Major - diagnosis</topic><topic>Depressive Disorder, Major - psychology</topic><topic>Diagnosis, Differential</topic><topic>Humans</topic><topic>Medical sciences</topic><topic>Mood disorders</topic><topic>Neuropsychological Tests - statistics & numerical data</topic><topic>Neuropsychology</topic><topic>Other psychotic disorders</topic><topic>Psychology. 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| ispartof | Journal of psychiatric research, 2004, Vol.38 (1), p.27-35 |
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| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Adult and adolescent clinical studies Affective Disorders, Psychotic - diagnosis Affective Disorders, Psychotic - psychology Biological and medical sciences Cognition Disorders - diagnosis Cognition Disorders - psychology Cognitive Cortisol Depression Depressive Disorder, Major - diagnosis Depressive Disorder, Major - psychology Diagnosis, Differential Humans Medical sciences Mood disorders Neuropsychological Tests - statistics & numerical data Neuropsychology Other psychotic disorders Psychology. Psychoanalysis. Psychiatry Psychometrics Psychopathology. Psychiatry Psychoses Psychotic Schizophrenia - diagnosis Schizophrenic Psychology |
| title | Neuropsychological correlates of psychotic features in major depressive disorders: a review and meta-analysis |
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