Transformation and DNA repair: linkage by DNA recombination
The stability of microbial genomes is constantly challenged by horizontal gene transfer, recombination and DNA damage. Mechanisms for rapid genome variation, adaptation and maintenance are a necessity to ensure microbial fitness and survival in changing environments. Indeed, genome sequences reveal...
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Veröffentlicht in: | Trends in microbiology (Regular ed.) 2004, Vol.12 (1), p.1-4 |
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description | The stability of microbial genomes is constantly challenged by horizontal gene transfer, recombination and DNA damage. Mechanisms for rapid genome variation, adaptation and maintenance are a necessity to ensure microbial fitness and survival in changing environments. Indeed, genome sequences reveal that most, if not all, bacterial species have numerous gene functions for DNA repair and recombination. These important topics were addressed at the Second Genome Maintenance Meeting (GMM2). |
doi_str_mv | 10.1016/j.tim.2003.11.008 |
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Mechanisms for rapid genome variation, adaptation and maintenance are a necessity to ensure microbial fitness and survival in changing environments. Indeed, genome sequences reveal that most, if not all, bacterial species have numerous gene functions for DNA repair and recombination. These important topics were addressed at the Second Genome Maintenance Meeting (GMM2).</description><subject>DNA Damage</subject><subject>DNA Repair</subject><subject>DNA, Bacterial - genetics</subject><subject>Genome, Bacterial</subject><subject>Recombination, Genetic</subject><subject>Transformation, Bacterial</subject><issn>0966-842X</issn><issn>1878-4380</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2004</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkE1Lw0AQhhdRbK3-AC-Sk7fEmf1INvYk9ROKXip4WzbJRrY2Sd1Nhf57tzbgTU8zDM_7MjyEnCMkCJheLZPeNgkFYAliAiAPyBhlJmPOJBySMeRpGktO30bkxPslAAhBxTEZIc_CztmYTBdOt77uXKN727WRbqvo9vkmcmatrbuOVrb90O8mKrbDueyawrY_8Ck5qvXKm7NhTsjr_d1i9hjPXx6eZjfzuAxv9DFDxoSBCkuhQRc6x8JomkshdM2prmohqayqQpscgdNUSKlzMGkmGE8LmbEJudz3rl33uTG-V431pVmtdGu6jVcSIMsA839BzCmGUh5A3IOl67x3plZrZxvttgpB7dSqpQpq1U6tQlRBbchcDOWbojHVb2JwGYDpHjDBxZc1TvnSmrY0lQ3aelV19o_6b6fph6E</recordid><startdate>2004</startdate><enddate>2004</enddate><creator>Tønjum, Tone</creator><creator>Håvarstein, Leiv S</creator><creator>Koomey, Michael</creator><creator>Seeberg, Erling</creator><general>Elsevier Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QL</scope><scope>C1K</scope><scope>7X8</scope></search><sort><creationdate>2004</creationdate><title>Transformation and DNA repair: linkage by DNA recombination</title><author>Tønjum, Tone ; Håvarstein, Leiv S ; Koomey, Michael ; Seeberg, Erling</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c380t-31335e0d1c5a0aba91bea29855af42adf5828ddbae910426588a90e675346b873</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2004</creationdate><topic>DNA Damage</topic><topic>DNA Repair</topic><topic>DNA, Bacterial - genetics</topic><topic>Genome, Bacterial</topic><topic>Recombination, Genetic</topic><topic>Transformation, Bacterial</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Tønjum, Tone</creatorcontrib><creatorcontrib>Håvarstein, Leiv S</creatorcontrib><creatorcontrib>Koomey, Michael</creatorcontrib><creatorcontrib>Seeberg, Erling</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Environmental Sciences and Pollution Management</collection><collection>MEDLINE - Academic</collection><jtitle>Trends in microbiology (Regular ed.)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Tønjum, Tone</au><au>Håvarstein, Leiv S</au><au>Koomey, Michael</au><au>Seeberg, Erling</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Transformation and DNA repair: linkage by DNA recombination</atitle><jtitle>Trends in microbiology (Regular ed.)</jtitle><addtitle>Trends Microbiol</addtitle><date>2004</date><risdate>2004</risdate><volume>12</volume><issue>1</issue><spage>1</spage><epage>4</epage><pages>1-4</pages><issn>0966-842X</issn><eissn>1878-4380</eissn><abstract>The stability of microbial genomes is constantly challenged by horizontal gene transfer, recombination and DNA damage. 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source | MEDLINE; ScienceDirect Journals (5 years ago - present) |
subjects | DNA Damage DNA Repair DNA, Bacterial - genetics Genome, Bacterial Recombination, Genetic Transformation, Bacterial |
title | Transformation and DNA repair: linkage by DNA recombination |
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