Pituitary Adenylate Cyclase-Activating Peptide: A Pivotal Modulator of Steroid-Induced Reproductive Behavior in Female Rodents

Pituitary adenylate cyclase-activating polypeptide (PACAP) regulates the secretion of GnRH into the hypothalamic hypophysial portal system and sensitizes the pituitary for release of hormones that trigger ovulation. Because reproductive behavior is synchronized with GnRH release, the present study w...

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Veröffentlicht in:	Molecular endocrinology (Baltimore, Md.) Md.), 2004-01, Vol.18 (1), p.173-183
Hauptverfasser:	Apostolakis, Ede Marie, Lanz, Rainer, O’Malley, Bert W
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Estrogens - pharmacology Female Mice Models, Animal Neuropeptides - genetics Neuropeptides - physiology Ovariectomy Pituitary Adenylate Cyclase-Activating Polypeptide Rats Rats, Sprague-Dawley Reproduction - drug effects Reproduction - physiology Reverse Transcriptase Polymerase Chain Reaction Sexual Behavior, Animal - physiology Ventromedial Hypothalamic Nucleus - drug effects Ventromedial Hypothalamic Nucleus - physiology
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