GTP modulates [ 125I]iodomelatonin binding to a picomolar-affinity site in the Syrian hamster hypothalamus

Saturation binding experiments conducted with [ 125I]iodomelatonin at 0–4°C in the Syrian hamster hypothalamus, revealed a single nanomolar-affinity site which was not affected by GTP. In contrast, incubation at 30°C revealed two distinct binding sites with picomolar and nanomolar affinities, respec...

Ausführliche Beschreibung