A novel protein crosslinking reagent for the determination of moderate resolution protein structures by mass spectrometry (MS3-D)

A new approach to the determination of moderate resolution protein structures, termed MS3-D—Mass Spectrometry in 3 Dimensions—has recently been disclosed. The method involves the formation of covalent crosslinks between reactive residues on the protein surface, the determination of the location of t...

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Veröffentlicht in:	Bioorganic & medicinal chemistry letters 2004-01, Vol.14 (2), p.427-429
Hauptverfasser:	Fujii, Naoaki, Jacobsen, Richard B., Wood, Nichole L., Schoeniger, Joseph S., Guy, R.Kiplin
Format:	Artikel
Sprache:	eng
Schlagworte:	Analytical, structural and metabolic biochemistry Biological and medical sciences Cross-Linking Reagents - chemical synthesis Fundamental and applied biological sciences. Psychology General aspects, investigation methods Mass Spectrometry - methods Protein Conformation Protein crosslinking affinity reagent MS3D Proteins Ubiquitin - analysis Ubiquitin - chemistry
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