Stimulation of the alpha-adrenoceptor triggers the venom production cycle in the venom gland of Bothrops jararaca

The noradrenergic innervation of Bothrops jararaca venom gland is thought to be important in the production and secretion of venom. We investigated the characteristics of the alpha-adrenoceptor in the venom gland and its role in venom production. This receptor had relatively low sensitivity to norad...

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Veröffentlicht in:	Journal of experimental biology 2004-01, Vol.207 (Pt 3), p.411-416
Hauptverfasser:	Kerchove, Celine M, Carneiro, Sylvia M, Markus, Regina P, Yamanouye, Norma
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bothrops - physiology Catecholamines - antagonists & inhibitors Crotalid Venoms - biosynthesis Crotalid Venoms - metabolism Dose-Response Relationship, Drug Exocrine Glands - metabolism Exocrine Glands - physiology Histological Techniques Norepinephrine - metabolism Phenylephrine - metabolism Receptors, Adrenergic, alpha - metabolism Reserpine - pharmacology
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