Persistent expression of the ATP-binding cassette transporter, Abcg2, identifies cardiac SP cells in the developing and adult heart

Stem cells are important in the maintenance and repair of adult tissues. A population of cells, termed side population (SP) cells, has stem cell characteristics as they have been shown to contribute to diverse lineages. In this study, we confirm that Abcg2 is a determinant of the SP cell phenotype....

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Veröffentlicht in:	Developmental biology 2004, Vol.265 (1), p.262-275
Hauptverfasser:	Martin, Cindy M., Meeson, Annette P., Robertson, Scott M., Hawke, Thomas J., Richardson, James A., Bates, Susan, Goetsch, Sean C., Gallardo, Teresa D., Garry, Daniel J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Abcg2 Animals ATP Binding Cassette Transporter, Subfamily G, Member 2 ATP-binding cassette transporter ATP-Binding Cassette Transporters - genetics ATP-Binding Cassette Transporters - physiology Blotting, Western Cardiac SP cells Cells, Cultured Gene Expression Profiling Gene Expression Regulation, Developmental Heart - physiology Immunohistochemistry In Situ Hybridization Mice Myocardium - cytology Neoplasm Proteins - genetics Neoplasm Proteins - physiology Reverse Transcriptase Polymerase Chain Reaction Stem Cells - physiology Yolk Sac - physiology
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