Patient-related variables and restenosis after percutaneous transluminal coronary angioplasty : a report from the M-HEART group
As part of a randomized prospective study designed to investigate the restenosis process after percutaneous transluminal coronary angioplasty (PTCA), the relation between patient-related variables and restenosis rate was examined. A total of 722 patients had successful PTCA. Angiographic follow-up w...
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| Veröffentlicht in: | The American journal of cardiology 1990-10, Vol.66 (12), p.926-931 |
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| container_title | The American journal of cardiology |
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| creator | MACDONALD, R. G HENDERSON, M. A HILL, J. A JUGO, R PEPINE, C. J HIRSHFELD, J. W GOLDBERG, S. H BASS, T VETROVEC, G COWLEY, M TAUSSIG, A WHITWORTH, H MARGOLIS, J. R |
| description | As part of a randomized prospective study designed to investigate the restenosis process after percutaneous transluminal coronary angioplasty (PTCA), the relation between patient-related variables and restenosis rate was examined. A total of 722 patients had successful PTCA. Angiographic follow-up was scheduled for 6 +/- 2 months after the procedure and achieved in 510 patients (71%), yielding 598 lesions for analysis. The overall restenosis rate was 40%. The rate was higher in patients undergoing early restudy for a clinical event than in those undergoing routinely scheduled follow-up restudy (71 vs 22%, p less than 0.0001). Age, sex, cigarette smoking history, diabetes mellitus and history of previous myocardial infarction were not associated with restenosis rate. Angina duration and severity before PTCA were also unrelated to restenosis rate. In summary, these variables, many of which have been previously implicated in restenosis, were not found to be predictors of restenosis. The decision to perform PTCA in individual patients should not be negatively influenced by the presence of these factors. |
| doi_str_mv | 10.1016/0002-9149(90)90927-S |
| format | Article |
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G ; HENDERSON, M. A ; HILL, J. A ; JUGO, R ; PEPINE, C. J ; HIRSHFELD, J. W ; GOLDBERG, S. H ; BASS, T ; VETROVEC, G ; COWLEY, M ; TAUSSIG, A ; WHITWORTH, H ; MARGOLIS, J. R</creator><creatorcontrib>MACDONALD, R. G ; HENDERSON, M. A ; HILL, J. A ; JUGO, R ; PEPINE, C. J ; HIRSHFELD, J. W ; GOLDBERG, S. H ; BASS, T ; VETROVEC, G ; COWLEY, M ; TAUSSIG, A ; WHITWORTH, H ; MARGOLIS, J. R</creatorcontrib><description>As part of a randomized prospective study designed to investigate the restenosis process after percutaneous transluminal coronary angioplasty (PTCA), the relation between patient-related variables and restenosis rate was examined. A total of 722 patients had successful PTCA. Angiographic follow-up was scheduled for 6 +/- 2 months after the procedure and achieved in 510 patients (71%), yielding 598 lesions for analysis. The overall restenosis rate was 40%. The rate was higher in patients undergoing early restudy for a clinical event than in those undergoing routinely scheduled follow-up restudy (71 vs 22%, p less than 0.0001). Age, sex, cigarette smoking history, diabetes mellitus and history of previous myocardial infarction were not associated with restenosis rate. Angina duration and severity before PTCA were also unrelated to restenosis rate. In summary, these variables, many of which have been previously implicated in restenosis, were not found to be predictors of restenosis. The decision to perform PTCA in individual patients should not be negatively influenced by the presence of these factors.</description><identifier>ISSN: 0002-9149</identifier><identifier>EISSN: 1879-1913</identifier><identifier>DOI: 10.1016/0002-9149(90)90927-S</identifier><identifier>PMID: 2220614</identifier><identifier>CODEN: AJCDAG</identifier><language>eng</language><publisher>New York, NY: Elsevier</publisher><subject>Adult ; Aged ; Aged, 80 and over ; Angioplasty, Balloon, Coronary ; Aspirin - administration & dosage ; Biological and medical sciences ; Cardiology. Vascular system ; Constriction, Pathologic - therapy ; Coronary Angiography ; Coronary Disease - complications ; Coronary Disease - diagnostic imaging ; Coronary Disease - therapy ; Coronary heart disease ; Diabetes Complications ; Drug Administration Schedule ; Female ; Follow-Up Studies ; Heart ; Humans ; Incidence ; Male ; Medical sciences ; Methylprednisolone - administration & dosage ; Middle Aged ; Prospective Studies ; Recurrence ; Smoking - epidemiology</subject><ispartof>The American journal of cardiology, 1990-10, Vol.66 (12), p.926-931</ispartof><rights>1991 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>315,781,785,27929,27930</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=19644634$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/2220614$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>MACDONALD, R. G</creatorcontrib><creatorcontrib>HENDERSON, M. A</creatorcontrib><creatorcontrib>HILL, J. A</creatorcontrib><creatorcontrib>JUGO, R</creatorcontrib><creatorcontrib>PEPINE, C. J</creatorcontrib><creatorcontrib>HIRSHFELD, J. W</creatorcontrib><creatorcontrib>GOLDBERG, S. H</creatorcontrib><creatorcontrib>BASS, T</creatorcontrib><creatorcontrib>VETROVEC, G</creatorcontrib><creatorcontrib>COWLEY, M</creatorcontrib><creatorcontrib>TAUSSIG, A</creatorcontrib><creatorcontrib>WHITWORTH, H</creatorcontrib><creatorcontrib>MARGOLIS, J. R</creatorcontrib><title>Patient-related variables and restenosis after percutaneous transluminal coronary angioplasty : a report from the M-HEART group</title><title>The American journal of cardiology</title><addtitle>Am J Cardiol</addtitle><description>As part of a randomized prospective study designed to investigate the restenosis process after percutaneous transluminal coronary angioplasty (PTCA), the relation between patient-related variables and restenosis rate was examined. A total of 722 patients had successful PTCA. Angiographic follow-up was scheduled for 6 +/- 2 months after the procedure and achieved in 510 patients (71%), yielding 598 lesions for analysis. The overall restenosis rate was 40%. The rate was higher in patients undergoing early restudy for a clinical event than in those undergoing routinely scheduled follow-up restudy (71 vs 22%, p less than 0.0001). Age, sex, cigarette smoking history, diabetes mellitus and history of previous myocardial infarction were not associated with restenosis rate. Angina duration and severity before PTCA were also unrelated to restenosis rate. In summary, these variables, many of which have been previously implicated in restenosis, were not found to be predictors of restenosis. The decision to perform PTCA in individual patients should not be negatively influenced by the presence of these factors.</description><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Angioplasty, Balloon, Coronary</subject><subject>Aspirin - administration & dosage</subject><subject>Biological and medical sciences</subject><subject>Cardiology. Vascular system</subject><subject>Constriction, Pathologic - therapy</subject><subject>Coronary Angiography</subject><subject>Coronary Disease - complications</subject><subject>Coronary Disease - diagnostic imaging</subject><subject>Coronary Disease - therapy</subject><subject>Coronary heart disease</subject><subject>Diabetes Complications</subject><subject>Drug Administration Schedule</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>Heart</subject><subject>Humans</subject><subject>Incidence</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Methylprednisolone - administration & dosage</subject><subject>Middle Aged</subject><subject>Prospective Studies</subject><subject>Recurrence</subject><subject>Smoking - epidemiology</subject><issn>0002-9149</issn><issn>1879-1913</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1990</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo9kE9r3DAQxUVISLebfoMUdElpD040tla2cgsh7RYSEvLnvIzk8cZBtlxJLuTUr17BLjkNj_ebB-8xdgriHASoCyFEWWiQ-rsWP7TQZV08HbAFNLUuQEN1yBYfyCf2Oca3LAFW6pgdl2UpFMgF-_eAqacxFYEcJmr5Xww9GkeR49jyQDHR6GOfZZco8ImCnROO5OfIU8AxunnoR3Tc-uBHDO_5b9v7yWFM7_ySY86YfEi8C37g6ZX4XbG-uXp85tvg5-mEHXXoIn3Z3yV7-XnzfL0ubu9__b6-ui0mUE0qoMO6koRGWNVWBFJKY7raWFqJptXQCmUaCxYRSlPJ1cqojprKStF2pSVTLdm3Xe4U_J85t9oMfbTk3K7KphGiBgkig1_34GwGajdT6IfcarNfLPtnex-jRdflCWwfPzDQSkpVyeo_K_x-Pg</recordid><startdate>19901015</startdate><enddate>19901015</enddate><creator>MACDONALD, R. 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Vascular system</topic><topic>Constriction, Pathologic - therapy</topic><topic>Coronary Angiography</topic><topic>Coronary Disease - complications</topic><topic>Coronary Disease - diagnostic imaging</topic><topic>Coronary Disease - therapy</topic><topic>Coronary heart disease</topic><topic>Diabetes Complications</topic><topic>Drug Administration Schedule</topic><topic>Female</topic><topic>Follow-Up Studies</topic><topic>Heart</topic><topic>Humans</topic><topic>Incidence</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Methylprednisolone - administration & dosage</topic><topic>Middle Aged</topic><topic>Prospective Studies</topic><topic>Recurrence</topic><topic>Smoking - epidemiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>MACDONALD, R. G</creatorcontrib><creatorcontrib>HENDERSON, M. A</creatorcontrib><creatorcontrib>HILL, J. A</creatorcontrib><creatorcontrib>JUGO, R</creatorcontrib><creatorcontrib>PEPINE, C. 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H</au><au>BASS, T</au><au>VETROVEC, G</au><au>COWLEY, M</au><au>TAUSSIG, A</au><au>WHITWORTH, H</au><au>MARGOLIS, J. R</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Patient-related variables and restenosis after percutaneous transluminal coronary angioplasty : a report from the M-HEART group</atitle><jtitle>The American journal of cardiology</jtitle><addtitle>Am J Cardiol</addtitle><date>1990-10-15</date><risdate>1990</risdate><volume>66</volume><issue>12</issue><spage>926</spage><epage>931</epage><pages>926-931</pages><issn>0002-9149</issn><eissn>1879-1913</eissn><coden>AJCDAG</coden><abstract>As part of a randomized prospective study designed to investigate the restenosis process after percutaneous transluminal coronary angioplasty (PTCA), the relation between patient-related variables and restenosis rate was examined. A total of 722 patients had successful PTCA. Angiographic follow-up was scheduled for 6 +/- 2 months after the procedure and achieved in 510 patients (71%), yielding 598 lesions for analysis. The overall restenosis rate was 40%. The rate was higher in patients undergoing early restudy for a clinical event than in those undergoing routinely scheduled follow-up restudy (71 vs 22%, p less than 0.0001). Age, sex, cigarette smoking history, diabetes mellitus and history of previous myocardial infarction were not associated with restenosis rate. Angina duration and severity before PTCA were also unrelated to restenosis rate. In summary, these variables, many of which have been previously implicated in restenosis, were not found to be predictors of restenosis. The decision to perform PTCA in individual patients should not be negatively influenced by the presence of these factors.</abstract><cop>New York, NY</cop><pub>Elsevier</pub><pmid>2220614</pmid><doi>10.1016/0002-9149(90)90927-S</doi><tpages>6</tpages></addata></record> |
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| ispartof | The American journal of cardiology, 1990-10, Vol.66 (12), p.926-931 |
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| subjects | Adult Aged Aged, 80 and over Angioplasty, Balloon, Coronary Aspirin - administration & dosage Biological and medical sciences Cardiology. Vascular system Constriction, Pathologic - therapy Coronary Angiography Coronary Disease - complications Coronary Disease - diagnostic imaging Coronary Disease - therapy Coronary heart disease Diabetes Complications Drug Administration Schedule Female Follow-Up Studies Heart Humans Incidence Male Medical sciences Methylprednisolone - administration & dosage Middle Aged Prospective Studies Recurrence Smoking - epidemiology |
| title | Patient-related variables and restenosis after percutaneous transluminal coronary angioplasty : a report from the M-HEART group |
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