Mechanical factors in large artery disease and antihypertensive drugs

Hypertension may induce early alterations in large arteries by 2 mechanical stresses: one related to intravascular pressure, the other to blood flow dynamics. Distending pressure force acts in a circumferential direction, inducing decreased arterial distensibility. Arterial distensibility can be eva...

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Veröffentlicht in:	The American journal of cardiology 1990-09, Vol.66 (9), p.C39-C42
Hauptverfasser:	Levenson, Jaime, Pithois-Merli, Isabelle, Simon, Alain
Format:	Artikel
Sprache:	eng
Schlagworte:	Antihypertensive Agents - therapeutic use Arteries - drug effects Arteries - physiopathology Biological and medical sciences Blood Flow Velocity - drug effects Blood Pressure - drug effects Blood Viscosity - drug effects Cardiology. Vascular system Compliance - drug effects Endothelium, Vascular - drug effects Humans Hypertension - blood Hypertension - drug therapy Hypertension - physiopathology Medical sciences
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