Position effect at S. cerevisiae telomeres: Reversible repression of Pol II transcription

S. cerevisiae chromosomes end with the telomeric repeat (TG 1–3) n. When any of four Pol II genes was placed immediately adjacent to the telomeric repeats, expression of the gene was reversibly repressed as demonstrated by phenotype and mRNA analyses. For example, cells bearing a telomere-linked cop...

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