Characterization of a Lineage‐Negative Stem‐Progenitor Cell Population Optimized for Ex Vivo Expansion and Enriched for LTC‐IC

Current hematopoietic stem cell transplantation protocols rely heavily upon CD34+ cells to estimate hematopoietic stem and progenitor cell (HSPC) yield. We and others previously reported CD133+ cells to represent a more primitive cell population than their CD34+ counterparts. However, both CD34+ and...

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Veröffentlicht in:	Stem cells (Dayton, Ohio) Ohio), 2004-01, Vol.22 (1), p.100-108
Hauptverfasser:	Forraz, Nicolas, Pettengell, Ruth, McGuckin, Colin P.
Format:	Artikel
Sprache:	eng
Schlagworte:	Antigens, Surface - immunology Biomarkers CD34 Cell Count Cell Culture Techniques - methods Cell Division - drug effects Cell Division - immunology Cell Lineage - immunology Cell Movement - drug effects Cell Movement - immunology Cell Separation - methods Cells, Cultured Cord Blood Stem Cell Transplantation - methods Culture Media - chemistry Culture Media - pharmacology Cytokines - pharmacology Ex vivo expansion Fetal Blood - cytology Fetal Blood - immunology Humans Infant, Newborn Leukocytes, Mononuclear - cytology Leukocytes, Mononuclear - immunology LTC‐IC Negative selection Stem cells Stem Cells - cytology Stem Cells - immunology Time
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