Comparison of Propofol and Thiopental/Halothane for Short-Duration ENT Surgical Procedures in Children
Experiences with propofol in pediatric anesthesia are limited. We undertook a study to evaluate the quality of induction and recovery from anesthesia with propofol compared to thiopental/halothane. Twenty children received 3 mg·kg·min of propofol as a loading dose followed by a maintenance dose of 0...
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| Veröffentlicht in: | Anesthesia and analgesia 1990-11, Vol.71 (5), p.511-515 |
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| creator | Borgeat, A. Popovic, V. Meier, D. Schwander, D. |
| description | Experiences with propofol in pediatric anesthesia are limited. We undertook a study to evaluate the quality of induction and recovery from anesthesia with propofol compared to thiopental/halothane. Twenty children received 3 mg·kg·min of propofol as a loading dose followed by a maintenance dose of 0.1 mg·kg·min (±10%). Twenty children received 5–7 mg/kg of thiopental, and maintenance was provided with halothane (0.5%–1.5%). The interval between the end of the administration of propofol or thiopental/halothane and extubation, as well to discharge to the ward, was significantly shorter with propofol (4.4 versus 13.5 min and 7.22 versus 30.4 min, respectively). Spontaneous movements and pain on injection were seen significantly more frequently with propofol, whereas laryngospasm and hiccup were only observed with thiopental. During the first 6 h after the surgical procedure, analgesics were needed significantly more often in the thiopental group. Nausea and vomiting also were observed more frequently in the thiopental group. In conclusion, propofol used as a single anesthetic is a satisfactory technique for ENT surgery of short duration in children. |
| doi_str_mv | 10.1213/00000539-199011000-00010 |
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We undertook a study to evaluate the quality of induction and recovery from anesthesia with propofol compared to thiopental/halothane. Twenty children received 3 mg·kg·min of propofol as a loading dose followed by a maintenance dose of 0.1 mg·kg·min (±10%). Twenty children received 5–7 mg/kg of thiopental, and maintenance was provided with halothane (0.5%–1.5%). The interval between the end of the administration of propofol or thiopental/halothane and extubation, as well to discharge to the ward, was significantly shorter with propofol (4.4 versus 13.5 min and 7.22 versus 30.4 min, respectively). Spontaneous movements and pain on injection were seen significantly more frequently with propofol, whereas laryngospasm and hiccup were only observed with thiopental. During the first 6 h after the surgical procedure, analgesics were needed significantly more often in the thiopental group. Nausea and vomiting also were observed more frequently in the thiopental group. In conclusion, propofol used as a single anesthetic is a satisfactory technique for ENT surgery of short duration in children.</description><identifier>ISSN: 0003-2999</identifier><identifier>EISSN: 1526-7598</identifier><identifier>DOI: 10.1213/00000539-199011000-00010</identifier><identifier>PMID: 2221411</identifier><identifier>CODEN: AACRAT</identifier><language>eng</language><publisher>Hagerstown, MD: International Anesthesia Research Society</publisher><subject>Anesthesia, Inhalation ; Anesthesia, Intravenous ; Anesthetics. Neuromuscular blocking agents ; Biological and medical sciences ; Child ; Child, Preschool ; Female ; Halothane ; Humans ; Male ; Medical sciences ; Neuropharmacology ; Otorhinolaryngologic Diseases - surgery ; Pharmacology. Drug treatments ; Propofol ; Thiopental ; Time Factors</subject><ispartof>Anesthesia and analgesia, 1990-11, Vol.71 (5), p.511-515</ispartof><rights>1990 International Anesthesia Research Society</rights><rights>1991 INIST-CNRS</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c5300-c7259444287a614488e4959f597f8a189ed93002b688e7f006d8f14ea32bba323</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttp://ovidsp.ovid.com/ovidweb.cgi?T=JS&NEWS=n&CSC=Y&PAGE=fulltext&D=ovft&AN=00000539-199011000-00010$$EHTML$$P50$$Gwolterskluwer$$H</linktohtml><link.rule.ids>314,776,780,4595,27901,27902,65206</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=19334874$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/2221411$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Borgeat, A.</creatorcontrib><creatorcontrib>Popovic, V.</creatorcontrib><creatorcontrib>Meier, D.</creatorcontrib><creatorcontrib>Schwander, D.</creatorcontrib><title>Comparison of Propofol and Thiopental/Halothane for Short-Duration ENT Surgical Procedures in Children</title><title>Anesthesia and analgesia</title><addtitle>Anesth Analg</addtitle><description>Experiences with propofol in pediatric anesthesia are limited. We undertook a study to evaluate the quality of induction and recovery from anesthesia with propofol compared to thiopental/halothane. Twenty children received 3 mg·kg·min of propofol as a loading dose followed by a maintenance dose of 0.1 mg·kg·min (±10%). Twenty children received 5–7 mg/kg of thiopental, and maintenance was provided with halothane (0.5%–1.5%). The interval between the end of the administration of propofol or thiopental/halothane and extubation, as well to discharge to the ward, was significantly shorter with propofol (4.4 versus 13.5 min and 7.22 versus 30.4 min, respectively). Spontaneous movements and pain on injection were seen significantly more frequently with propofol, whereas laryngospasm and hiccup were only observed with thiopental. During the first 6 h after the surgical procedure, analgesics were needed significantly more often in the thiopental group. Nausea and vomiting also were observed more frequently in the thiopental group. In conclusion, propofol used as a single anesthetic is a satisfactory technique for ENT surgery of short duration in children.</description><subject>Anesthesia, Inhalation</subject><subject>Anesthesia, Intravenous</subject><subject>Anesthetics. Neuromuscular blocking agents</subject><subject>Biological and medical sciences</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>Female</subject><subject>Halothane</subject><subject>Humans</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Neuropharmacology</subject><subject>Otorhinolaryngologic Diseases - surgery</subject><subject>Pharmacology. Drug treatments</subject><subject>Propofol</subject><subject>Thiopental</subject><subject>Time Factors</subject><issn>0003-2999</issn><issn>1526-7598</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1990</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kV1PwyAYhYnRzDn9CSbc6F1d-WgLl2ZOZ7KoyeY1YS1YlJUKbRb_vexDvZIECLzPOcABAIjSG4QRGafblhGeIM5ThOIiiR2lR2CIMpwnRcbZMRjGPZJgzvkpOAvhfYewfAAGGGNEERoCPXHrVnoTXAOdhi_etU47C2VTwWVtXKuaTtrxTFrX1bJRUDsPF7XzXXLXe9mZqJs-LeGi92-mlHbrUKqq9ypA08BJbWzlVXMOTrS0QV0c5hF4vZ8uJ7Nk_vzwOLmdJ2VG4hvKAmecUopZIXNEKWOK8ozrjBeaScS4qnjk8CqPlUKnaV4xjaiSBK9WcSAjcL33bb377FXoxNqEUlkbr-76IFiUbN0jyPZg6V0IXmnRerOW_kugVGwjFj8Ri9-IxS6_KL08nNGv1qr6FR4yjfWrQ12GmIj2silN-PPnhFBW0MjRPbdxtlM-fNh-o7yolbRdLf77YfIN2uySBQ</recordid><startdate>199011</startdate><enddate>199011</enddate><creator>Borgeat, A.</creator><creator>Popovic, V.</creator><creator>Meier, D.</creator><creator>Schwander, D.</creator><general>International Anesthesia Research Society</general><general>Lippincott</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>199011</creationdate><title>Comparison of Propofol and Thiopental/Halothane for Short-Duration ENT Surgical Procedures in Children</title><author>Borgeat, A. ; Popovic, V. ; Meier, D. ; Schwander, D.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c5300-c7259444287a614488e4959f597f8a189ed93002b688e7f006d8f14ea32bba323</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1990</creationdate><topic>Anesthesia, Inhalation</topic><topic>Anesthesia, Intravenous</topic><topic>Anesthetics. Neuromuscular blocking agents</topic><topic>Biological and medical sciences</topic><topic>Child</topic><topic>Child, Preschool</topic><topic>Female</topic><topic>Halothane</topic><topic>Humans</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Neuropharmacology</topic><topic>Otorhinolaryngologic Diseases - surgery</topic><topic>Pharmacology. Drug treatments</topic><topic>Propofol</topic><topic>Thiopental</topic><topic>Time Factors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Borgeat, A.</creatorcontrib><creatorcontrib>Popovic, V.</creatorcontrib><creatorcontrib>Meier, D.</creatorcontrib><creatorcontrib>Schwander, D.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Anesthesia and analgesia</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Borgeat, A.</au><au>Popovic, V.</au><au>Meier, D.</au><au>Schwander, D.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Comparison of Propofol and Thiopental/Halothane for Short-Duration ENT Surgical Procedures in Children</atitle><jtitle>Anesthesia and analgesia</jtitle><addtitle>Anesth Analg</addtitle><date>1990-11</date><risdate>1990</risdate><volume>71</volume><issue>5</issue><spage>511</spage><epage>515</epage><pages>511-515</pages><issn>0003-2999</issn><eissn>1526-7598</eissn><coden>AACRAT</coden><abstract>Experiences with propofol in pediatric anesthesia are limited. We undertook a study to evaluate the quality of induction and recovery from anesthesia with propofol compared to thiopental/halothane. Twenty children received 3 mg·kg·min of propofol as a loading dose followed by a maintenance dose of 0.1 mg·kg·min (±10%). Twenty children received 5–7 mg/kg of thiopental, and maintenance was provided with halothane (0.5%–1.5%). The interval between the end of the administration of propofol or thiopental/halothane and extubation, as well to discharge to the ward, was significantly shorter with propofol (4.4 versus 13.5 min and 7.22 versus 30.4 min, respectively). Spontaneous movements and pain on injection were seen significantly more frequently with propofol, whereas laryngospasm and hiccup were only observed with thiopental. During the first 6 h after the surgical procedure, analgesics were needed significantly more often in the thiopental group. Nausea and vomiting also were observed more frequently in the thiopental group. In conclusion, propofol used as a single anesthetic is a satisfactory technique for ENT surgery of short duration in children.</abstract><cop>Hagerstown, MD</cop><pub>International Anesthesia Research Society</pub><pmid>2221411</pmid><doi>10.1213/00000539-199011000-00010</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record> |
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| ispartof | Anesthesia and analgesia, 1990-11, Vol.71 (5), p.511-515 |
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| source | MEDLINE; Journals@Ovid LWW Legacy Archive; EZB-FREE-00999 freely available EZB journals; Journals@Ovid Complete |
| subjects | Anesthesia, Inhalation Anesthesia, Intravenous Anesthetics. Neuromuscular blocking agents Biological and medical sciences Child Child, Preschool Female Halothane Humans Male Medical sciences Neuropharmacology Otorhinolaryngologic Diseases - surgery Pharmacology. Drug treatments Propofol Thiopental Time Factors |
| title | Comparison of Propofol and Thiopental/Halothane for Short-Duration ENT Surgical Procedures in Children |
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