Measuring departures from Hardy-Weinberg: a Markov chain Monte Carlo method for estimating the inbreeding coefficient

Many well-established statistical methods in genetics were developed in a climate of severe constraints on computational power. Recent advances in simulation methodology now bring modern, flexible statistical methods within the reach of scientists having access to a desktop workstation. We illustrat...

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Veröffentlicht in:	Heredity 1998-06, Vol.80 (6), p.769-777
Hauptverfasser:	Ayres, Karen L, Balding, David J
Format:	Artikel
Sprache:	eng
Schlagworte:	Algorithms Alleles Animals Bayesian statistics Biomedical and Life Sciences Biomedicine Consanguinity Cytogenetics Ecology Evolutionary Biology Hardy–Weinberg Human Genetics Humans Inbreeding inbreeding coefficient inbreeding model Markov chain Monte Carlo Markov Chains Metropolis–Hastings algorithm Models, Genetic Models, Statistical Monte Carlo Method New Zealand original-article Plant Genetics and Genomics Samoa - ethnology
Online-Zugang:	Volltext
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