Differences in a dinucleotide repeat polymorphism in the tau gene between Caucasian and Japanese populations: implication for progressive supranuclear palsy

Previous studies of a tau polymorphism in Caucasian subjects with progressive supranuclear palsy (PSP) showed an over-representation of one genotype, A0/A0, versus normal control subjects. This result suggested that tau may be playing a genetic role in the progression of PSP. This study examines whe...

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Veröffentlicht in:	Neuroscience letters 1998-07, Vol.250 (2), p.135-137
Hauptverfasser:	Conrad, Chris, Amano, Naoji, Andreadis, Athena, Xia, Yu, Namekataf, Kazuhiko, Oyama, Fumitaka, Ikeda, Kenji, Wakabayashi, Koichi, Takahashi, Hitoshi, J. Thal, Leon, Katzman, Robert, Shackelford, Deborah A, Matsushita, Masaaki, Masliah, Eliezer, Sawa, Akira
Format:	Artikel
Sprache:	eng
Schlagworte:	Alzheimer Disease - genetics Alzheimer's disease Asian Continental Ancestry Group - genetics Biological and medical sciences Caucasian Chromosome 17 Chromosomes, Human, Pair 17 - genetics Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases Dinucleotide repeat Dinucleotide Repeats - genetics European Continental Ancestry Group - genetics Exon 10 Humans Intron Japan Japanese Medical sciences Neurology Polymorphism, Genetic - genetics Progressive supranuclear palsy Supranuclear Palsy, Progressive - genetics Tau tau Proteins - genetics
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