Cerebrospinal fluid prostaglandins after systemic dipyrone intake

Objective The object of this study was to evaluate the time course of thromboxane B2 and prostaglandin E2 concentrations in cerebrospinal fluid after oral administration of dipyrone (INN, metamizole). Methods A single 1.0 gm oral dose of dipyrone was given to consenting patients undergoing elective...

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Veröffentlicht in:	Clinical pharmacology and therapeutics 1998-07, Vol.64 (1), p.117-122
Hauptverfasser:	Levy, Micha, Brune, Kay, Zylber‐Katz, Ester, Cohen, Oren, Caraco, Yoseph, Geisslinger, Gerd
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Oral Adolescent Adult Aged Aged, 80 and over Analgesics Anti-Inflammatory Agents, Non-Steroidal - administration & dosage Anti-Inflammatory Agents, Non-Steroidal - pharmacology Biological and medical sciences Child Child, Preschool Dinoprostone - cerebrospinal fluid Dipyrone - administration & dosage Dipyrone - pharmacology Female Humans Infant Male Medical sciences Middle Aged Neuropharmacology Pharmacology. Drug treatments Thromboxane B2 - cerebrospinal fluid Time Factors
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