Squamous Cell Carcinoma of the Skin Associated with Systemic Sclerosis

background. The coexistence of systemic sclerosis and cancer has been recognized with increasing frequency. However, squamous cell carcinoma of the skin associated with systemic sclerosis is relatively rare. objective. The mechanisms of malignancy in systemic sclerosis are discussed. methods. An 18‐...

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Veröffentlicht in:Dermatologic surgery 1998-07, Vol.24 (7), p.777-779
Hauptverfasser: ÖZTÜRK, MEHMET AKIF, BENEKLI, MUSTAFA, ALTUNDAĜ, MUSTAFA KADRI, GÜLER, NILÜFER
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container_end_page 779
container_issue 7
container_start_page 777
container_title Dermatologic surgery
container_volume 24
creator ÖZTÜRK, MEHMET AKIF
BENEKLI, MUSTAFA
ALTUNDAĜ, MUSTAFA KADRI
GÜLER, NILÜFER
description background. The coexistence of systemic sclerosis and cancer has been recognized with increasing frequency. However, squamous cell carcinoma of the skin associated with systemic sclerosis is relatively rare. objective. The mechanisms of malignancy in systemic sclerosis are discussed. methods. An 18‐year‐old girl with progressive systemic sclerosis is described. results. The patient had developed squamous cell carcinoma of the skin on the sclerosed skin of her left leg requiring amputation. The tumor recurred on the distal end of the stump. Local radiotherapy was unsuccessful. conclusion. This report suggests that sclerosis of the skin may manifest a greater risk of developing skin cancers unrelated to chronic injury or scarring of the skin.© 1998 by the American Society for Dermatologic Surgery, Inc.
doi_str_mv 10.1111/j.1524-4725.1998.tb04249.x
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The coexistence of systemic sclerosis and cancer has been recognized with increasing frequency. However, squamous cell carcinoma of the skin associated with systemic sclerosis is relatively rare. objective. The mechanisms of malignancy in systemic sclerosis are discussed. methods. An 18‐year‐old girl with progressive systemic sclerosis is described. results. The patient had developed squamous cell carcinoma of the skin on the sclerosed skin of her left leg requiring amputation. The tumor recurred on the distal end of the stump. Local radiotherapy was unsuccessful. conclusion. 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The coexistence of systemic sclerosis and cancer has been recognized with increasing frequency. However, squamous cell carcinoma of the skin associated with systemic sclerosis is relatively rare. objective. The mechanisms of malignancy in systemic sclerosis are discussed. methods. An 18‐year‐old girl with progressive systemic sclerosis is described. results. The patient had developed squamous cell carcinoma of the skin on the sclerosed skin of her left leg requiring amputation. The tumor recurred on the distal end of the stump. Local radiotherapy was unsuccessful. conclusion. 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Vasculitis</subject><subject>Scleroderma, Systemic - pathology</subject><subject>Skin Neoplasms - pathology</subject><subject>Skin Neoplasms - radiotherapy</subject><subject>Skin Neoplasms - surgery</subject><subject>Tropical medicine</subject><issn>1076-0512</issn><issn>1524-4725</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1998</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqVkF9LwzAUxYMoOqcfQQgivrXmJm2T-CDI_AsDH6rPIU1TltmuW9Oh-_amrOzdvNzAOffec38IXQOJIby7ZQwpTaKE0zQGKUXcFyShiYx_j9DkIB2HP-FZRFKgZ-jc-yUhQCUjp-hUZpJlPJmgl3yz1U279Xhm6xrPdGfcqm00bivcLyzOv90KP3rfGqd7W-If1y9wvvO9bZzBualt13rnL9BJpWtvL8c6RV8vz5-zt2j-8fo-e5xHhknBI0GgAs2ELEWRJZRJq1MKsuCccJ1pRmgKGQUmjKgsLSWUWgKQklFSpAQMm6Lb_dx112621veqcd6E5HplwxFKkHAtcBqM93ujCfl8Zyu17lyju50CogaIaqkGUmogpQaIaoSofkPz1bhlWzS2PLSO1IJ-M-raG11XnV4Z5w82yhKgYrA97G0_rra7fwRQT_kX55z9AfVWjLU</recordid><startdate>199807</startdate><enddate>199807</enddate><creator>ÖZTÜRK, MEHMET AKIF</creator><creator>BENEKLI, MUSTAFA</creator><creator>ALTUNDAĜ, MUSTAFA KADRI</creator><creator>GÜLER, NILÜFER</creator><general>Blackwell Publishing Ltd</general><general>Blackwell</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>199807</creationdate><title>Squamous Cell Carcinoma of the Skin Associated with Systemic Sclerosis</title><author>ÖZTÜRK, MEHMET AKIF ; BENEKLI, MUSTAFA ; ALTUNDAĜ, MUSTAFA KADRI ; GÜLER, NILÜFER</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3987-801f1a389d8b64239ea5219b7707a6a3025162138c8fe2d91da9110d320b501c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1998</creationdate><topic>Adolescent</topic><topic>Amputation</topic><topic>Biological and medical sciences</topic><topic>Carcinoma, Squamous Cell - pathology</topic><topic>Carcinoma, Squamous Cell - radiotherapy</topic><topic>Carcinoma, Squamous Cell - surgery</topic><topic>Female</topic><topic>Humans</topic><topic>Leg - surgery</topic><topic>Leg Ulcer - pathology</topic><topic>Leg Ulcer - surgery</topic><topic>Medical sciences</topic><topic>Neoplasm Recurrence, Local - pathology</topic><topic>Neoplasm Recurrence, Local - radiotherapy</topic><topic>Sarcoidosis. 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The coexistence of systemic sclerosis and cancer has been recognized with increasing frequency. However, squamous cell carcinoma of the skin associated with systemic sclerosis is relatively rare. objective. The mechanisms of malignancy in systemic sclerosis are discussed. methods. An 18‐year‐old girl with progressive systemic sclerosis is described. results. The patient had developed squamous cell carcinoma of the skin on the sclerosed skin of her left leg requiring amputation. The tumor recurred on the distal end of the stump. Local radiotherapy was unsuccessful. conclusion. This report suggests that sclerosis of the skin may manifest a greater risk of developing skin cancers unrelated to chronic injury or scarring of the skin.© 1998 by the American Society for Dermatologic Surgery, Inc.</abstract><cop>Oxford, UK</cop><pub>Blackwell Publishing Ltd</pub><pmid>9693674</pmid><doi>10.1111/j.1524-4725.1998.tb04249.x</doi><tpages>3</tpages></addata></record>
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source MEDLINE; Wiley Online Library Journals Frontfile Complete; Journals@Ovid Complete
subjects Adolescent
Amputation
Biological and medical sciences
Carcinoma, Squamous Cell - pathology
Carcinoma, Squamous Cell - radiotherapy
Carcinoma, Squamous Cell - surgery
Female
Humans
Leg - surgery
Leg Ulcer - pathology
Leg Ulcer - surgery
Medical sciences
Neoplasm Recurrence, Local - pathology
Neoplasm Recurrence, Local - radiotherapy
Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis
Scleroderma, Systemic - pathology
Skin Neoplasms - pathology
Skin Neoplasms - radiotherapy
Skin Neoplasms - surgery
Tropical medicine
title Squamous Cell Carcinoma of the Skin Associated with Systemic Sclerosis
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