Hyperpolarization of myenteric neurons by opioids does not involve cyclic adenosine-3′,5′-monophosphate

To investigate the role of cyclic adenosine-3′,5′-monophosphate on the inhibitory actions of opioids in guinea-pig ileum, we made intracellular recordings from the two electrophysiologically defined classes of neurons (S and AH) in the myenteric plexus. The selective opioid mu agonist (d-Ala2,N-Me-P...

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